Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) for PDB: 2OF4
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM17714(5,6-diphenyl-N-[2-(piperazin-1-yl)ethyl]furo[2,3-d...)
Show SMILES C(CN1CCNCC1)Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1
Show InChI InChI=1S/C24H25N5O/c1-3-7-18(8-4-1)20-21-23(26-13-16-29-14-11-25-12-15-29)27-17-28-24(21)30-22(20)19-9-5-2-6-10-19/h1-10,17,25H,11-16H2,(H,26,27,28)
Affinity DataIC50: 81nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM17714(5,6-diphenyl-N-[2-(piperazin-1-yl)ethyl]furo[2,3-d...)
Show SMILES C(CN1CCNCC1)Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1
Show InChI InChI=1S/C24H25N5O/c1-3-7-18(8-4-1)20-21-23(26-13-16-29-14-11-25-12-15-29)27-17-28-24(21)30-22(20)19-9-5-2-6-10-19/h1-10,17,25H,11-16H2,(H,26,27,28)
Affinity DataIC50: 81nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair