Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) for PDB: 4ALW
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Exelixis Inc

Curated by ChEMBL
Show SMILES CN1CCN(Cc2nc3c4cc(Br)ccc4oc3c(=O)[nH]2)CC1
Show InChI InChI=1S/C16H17BrN4O2/c1-20-4-6-21(7-5-20)9-13-18-14-11-8-10(17)2-3-12(11)23-15(14)16(22)19-13/h2-3,8H,4-7,9H2,1H3,(H,18,19,22)
Affinity DataIC50: 27nMAssay Description:Inhibition of N-terminal His-tagged human PIM1 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by luciferasse-luciferin-co...More data for this Ligand-Target Pair