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Compile Data Set for Download or QSAR
maximum 50k data
Found
1
Enz. Inhib. hit(s) for PDB:
4R5Y
Target
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human))
Temple University
Curated by
ChEMBL
Ligand
BDBM50453816
(BGB-283 | Bgb 283 | Lifirafenib)
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Affinity Data
IC50: 23nM
Assay Description:
Inhibition of BRAF (unknown origin) using MEK1 K97R mutant as substrate preincubated for 60 to 120 mins followed by substrate addition measured after...
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Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Ligand Info
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PC cid
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PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
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