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Found 32 Enz. Inhib. hit(s) with Target = 'ATP-dependent Clp protease ATP-binding subunit ClpC1'
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM213240(Cyclomarin A1 (CymA1))
Affinity DataKd:  17.5nMpH: 7.5 T: 2°CAssay Description:Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540283(CHEMBL4643756)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1 [1-493](Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM213240(Cyclomarin A1 (CymA1))
Affinity DataKd:  19.2nMpH: 7.5 T: 2°CAssay Description:Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1 [1-145,F2A](Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM213240(Cyclomarin A1 (CymA1))
Affinity DataKd:  3.90E+3nMpH: 7.5 T: 2°CAssay Description:Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1 [1-145,F80A](Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM213240(Cyclomarin A1 (CymA1))
Affinity DataKd:  2.10E+3nMpH: 7.5 T: 2°CAssay Description:Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1 [1-145,E89A](Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM213240(Cyclomarin A1 (CymA1))
Affinity DataKd:  127nMpH: 7.5 T: 2°CAssay Description:Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1 [1-145,F2Y](Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM213240(Cyclomarin A1 (CymA1))
Affinity DataKd:  780nMpH: 7.5 T: 2°CAssay Description:Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1 [1-145,F80Y](Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM213240(Cyclomarin A1 (CymA1))
Affinity DataKd:  124nMpH: 7.5 T: 2°CAssay Description:Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1 [1-145,E89Q](Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM213240(Cyclomarin A1 (CymA1))
Affinity DataKd:  65nMpH: 7.5 T: 2°CAssay Description:Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540273(CHEMBL4637575)
Affinity DataKd:  620nMAssay Description:Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540274(CHEMBL4641855)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540275(CHEMBL4649631)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540276(CHEMBL4643598)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540277(CHEMBL4649342)
Affinity DataKd:  310nMAssay Description:Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540278(CHEMBL4647204)
Affinity DataKd:  300nMAssay Description:Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540279(CHEMBL4637113)
Affinity DataKd:  60nMAssay Description:Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540280(CHEMBL4648320)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540281(CHEMBL4642233)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540282(CHEMBL4638710)
Affinity DataKd:  60nMAssay Description:Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540283(CHEMBL4643756)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540273(CHEMBL4637575)
Affinity DataKd:  500nMAssay Description:Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540274(CHEMBL4641855)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540275(CHEMBL4649631)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540276(CHEMBL4643598)
Affinity DataKd:  5.70E+3nMAssay Description:Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540277(CHEMBL4649342)
Affinity DataKd:  450nMAssay Description:Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540284(CHEMBL4636448)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540278(CHEMBL4647204)
Affinity DataKd:  280nMAssay Description:Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540279(CHEMBL4637113)
Affinity DataKd:  50nMAssay Description:Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540280(CHEMBL4648320)
Affinity DataKd:  540nMAssay Description:Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540281(CHEMBL4642233)
Affinity DataKd:  3.20E+3nMAssay Description:Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1(Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM50540282(CHEMBL4638710)
Affinity DataKd:  60nMAssay Description:Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent Clp protease ATP-binding subunit ClpC1 [1-145](Mycobacterium tuberculosis)
Novartis Institute For Tropical Diseases

LigandPNGBDBM213240(Cyclomarin A1 (CymA1))
Affinity DataKd:  12nMpH: 7.5 T: 2°CAssay Description:Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed