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Found 20 Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein [1-42]'
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50492518(Florbetapir | US10906900, AV45)
Affinity DataKi:  2.20nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50185987(2-(1-(6-((2-fluoroethyl)(methyl)amino)naphthalen-2...)
Affinity DataKi:  4.60nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481151(US10906900, Reference 22c)
Affinity DataKi:  21.3nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481149(US10906900, Reference 22a)
Affinity DataKi:  24.5nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481150(US10906900, Reference 22b)
Affinity DataKi:  91.5nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481155(US10906900, Reference 22h)
Affinity DataKi:  244nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481154(US10906900, Reference 22g)
Affinity DataKi:  318nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481153(US10906900, Reference 22f)
Affinity DataKi:  349nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481152(US10906900, Reference 22e)
Affinity DataKi:  909nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481159(US10906900, Reference 25c)
Affinity DataKd:  3.10nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481158(US10906900, Reference 25b)
Affinity DataKd:  4.27nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481157(US10906900, Reference 25a)
Affinity DataKd:  4.90nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481153(US10906900, Reference 22f)
Affinity DataKd:  16.8nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481156(US10906900, Reference 22d)
Affinity DataKd:  3.60nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481151(US10906900, Reference 22c)
Affinity DataKd:  2.90nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481150(US10906900, Reference 22b)
Affinity DataKd:  5.20nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481149(US10906900, Reference 22a)
Affinity DataKd:  11.8nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50185987(2-(1-(6-((2-fluoroethyl)(methyl)amino)naphthalen-2...)
Affinity DataKd:  4.20nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481160(US10906900, Reference 28)
Affinity DataKd:  1.20nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50492518(Florbetapir | US10906900, AV45)
Affinity DataKd:  1.68nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In DepthDetails US Patent