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Found 4439 Enz. Inhib. hit(s) with Target = 'D(4) dopamine receptor'
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50122050(CHEMBL156599 | N-{2-[4-(2,3-Dichloro-phenyl)-piper...)
Affinity DataKi:  0.0180nMAssay Description:Binding affinity towards human Dopamine receptor D4 using [3H]spiroperidol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50122028(3-Methoxy-N-[2-(4-p-tolyl-piperazin-1-yl)-ethyl]-b...)
Affinity DataKi:  0.0250nMAssay Description:Binding affinity towards human Dopamine receptor D4 using [3H]spiroperidol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50530438(Mosapramine | Mosapramine hydrochloride)
Affinity DataKi:  0.0300nMAssay Description:Agonist activity at dopamine D4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50005120(CHEMBL274491 | N-((2S,3S)-1-Benzyl-2-methyl-pyrrol...)
Affinity DataKi:  0.0300nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50005120(CHEMBL274491 | N-((2S,3S)-1-Benzyl-2-methyl-pyrrol...)
Affinity DataKi:  0.0300nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50530438(Mosapramine | Mosapramine hydrochloride)
Affinity DataKi:  0.0300nMAssay Description:Agonist activity at dopamine D4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50068366(CHEMBL93403 | N-{2-[4-(4-Chloro-phenyl)-piperazin-...)
Affinity DataKi:  0.0400nMAssay Description:In vitro binding affinity at human Dopamine receptor D4.4 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50122026(CHEMBL157322 | N-{2-[4-(2-Chloro-phenyl)-piperazin...)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity towards human Dopamine receptor D4 using [3H]spiroperidol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50068366(CHEMBL93403 | N-{2-[4-(4-Chloro-phenyl)-piperazin-...)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity towards human Dopamine receptor D4 using [3H]spiroperidol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.0500nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM81492(BENPERIDOL | CAS_2062-84-2 | NSC_16363)
Affinity DataKi:  0.0660nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50183266(Anquil | Benperidol | Benquil | MCN-JR-4584 | R-45...)
Affinity DataKi:  0.0660nMAssay Description:Binding affinity to human dopamine D4 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.0800nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM85223(CAS_115368 | NSC_115368 | Perospirone)
Affinity DataKi:  0.0900nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.0900nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50005120(CHEMBL274491 | N-((2S,3S)-1-Benzyl-2-methyl-pyrrol...)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50122032(3-Methoxy-N-[2-(4-naphthalen-1-yl-piperazin-1-yl)-...)
Affinity DataKi:  0.210nMAssay Description:Binding affinity towards human Dopamine receptor D4 using [3H]spiroperidol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  0.230nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50505700(CHEMBL4442460)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50189854(6-bromo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl...)
Affinity DataKi:  0.25nMAssay Description:Agonist activity at dopamine D4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50001885((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
Affinity DataKi:  0.25nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50189854(6-bromo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50001885((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
Affinity DataKi:  0.25nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50189854(6-bromo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl...)
Affinity DataKi:  0.25nMAssay Description:Agonist activity at dopamine D4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50122047(CHEMBL157388 | N-{2-[4-(3-Chloro-phenyl)-piperazin...)
Affinity DataKi:  0.260nMAssay Description:Binding affinity towards human Dopamine receptor D4 using [3H]spiroperidol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50184795(1-(2-methoxyphenyl)-4-((1-phenyl-1H-pyrazol-4-yl)m...)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM85222(CAS_441351-20-8 | Lurasidone | SM 13496)
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50061349(CHEMBL129534 | [2-(3-Chloro-phenoxy)-ethyl]-(3-phe...)
Affinity DataKi:  0.309nMAssay Description:Binding affinity to displace [3H]spiperone from cloned human dopamine receptor D4 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.310nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50061349(CHEMBL129534 | [2-(3-Chloro-phenoxy)-ethyl]-(3-phe...)
Affinity DataKi:  0.310nMAssay Description:Binding affinity to recombinant human dopamine receptor D4 expressed in CHO cells by displacement of [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.310nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50189841(6-iodo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]...)
Affinity DataKi:  0.330nMAssay Description:Agonist activity at dopamine D4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50189841(6-iodo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]...)
Affinity DataKi:  0.330nMAssay Description:Agonist activity at dopamine D4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.330nMAssay Description:Biniding affinity for Dopamine receptor D4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50079161(5-Methyl-1-[1-(3-methyl-benzyl)-piperidin-4-yl]-4-...)
Affinity DataKi:  0.330nMAssay Description:Affinity to displace [3H]-spiperone from cloned human Dopamine receptor D4 stably expressed in HEK-393 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50257034(CHEMBL4096543)
Affinity DataKi:  0.330nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50189841(6-iodo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50257034(CHEMBL4096543)
Affinity DataKi:  0.331nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D4 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50329410(CHEMBL1270323 | N-(2-(4-(benzo[d]isoxazol-3-yl)pip...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]MSP from rat dopamine D4 receptor expressed in HEK293 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50061345(CHEMBL129927 | [2-(3,4-Dimethyl-phenoxy)-ethyl]-(3...)
Affinity DataKi:  0.347nMAssay Description:Binding affinity to displace [3H]spiperone from cloned human dopamine receptor D4 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.350nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50061345(CHEMBL129927 | [2-(3,4-Dimethyl-phenoxy)-ethyl]-(3...)
Affinity DataKi:  0.350nMAssay Description:Binding affinity to recombinant human dopamine receptor D4 expressed in CHO cells by displacement of [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM81493(CAS_749-13-3 | TRIFLUORPERIDOL)
Affinity DataKi:  0.350nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50167934(CHEMBL191962 | N-{4-[4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  0.370nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D4.4 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50077001(1-Benzyl-4-(3-methyl-4-phenyl-pyrazol-1-yl)-piperi...)
Affinity DataKi:  0.390nMAssay Description:Binding affinity of compound towards human Dopamine receptor D4 by displacing [125I]-iodosulpiride expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50077001(1-Benzyl-4-(3-methyl-4-phenyl-pyrazol-1-yl)-piperi...)
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]-spiperone from human Dopamine receptor D4 expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(RAT)
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.390nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM85093(CAS_3853 | CHEMBL267014 | CHEMBL555670 | L 745,870...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM22872(1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-y...)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universit£ degli Studi di Bari

Curated by ChEMBL
LigandPNGBDBM50589760(CHEMBL5198170)
Affinity DataKi:  0.407nMAssay Description:Displacement of [3H]N-methylspiperone from human D4.4 receptor expressed in HEK293T cell membrane incubated for 1 hr by MicroBeta scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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