Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 9107
TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442057BDBM442057(24(1-acetylpiperidin-4-yl)amino)-N-(4-(3,4-dihydro...)
Affinity DataIC50: 186nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442031BDBM442031(US10647708, Compound 20)
Affinity DataIC50: 214nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442030BDBM442030(US10647708, Compound 19)
Affinity DataIC50: 319nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 441959BDBM441959(4-Chloro-N-(4-(3,4-dihydroisoquinolin-2(1H)-yl)-3-...)
Affinity DataIC50: 359nMAssay Description:The κ uL assay reactions are run in Greiner brand black 384-well low volume plates. All reactions contained assay buffer (phosphate buffered sa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442032BDBM442032(US10647708, Compound 21)
Affinity DataIC50: 415nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442051BDBM442051(US10647708, Compound 40)
Affinity DataIC50: 769nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442024BDBM442024(US10647708, Compound 14)
Affinity DataIC50: 910nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442012BDBM442012(US10647708, Compound 3)
Affinity DataIC50: 925nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442011BDBM442011(US10647708, Compound 2)
Affinity DataIC50: 1.13E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442048BDBM442048(US10647708, Compound 37)
Affinity DataIC50: 1.19E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442047BDBM442047(US10647708, Compound 36)
Affinity DataIC50: 1.20E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442046BDBM442046(US10647708, Compound 35)
Affinity DataIC50: 1.21E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442050BDBM442050(US10647708, Compound 39)
Affinity DataIC50: 1.22E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442014BDBM442014(US10647708, Compound 5)
Affinity DataIC50: 1.33E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442022BDBM442022(US10647708, Compound 12)
Affinity DataIC50: 1.60E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442034BDBM442034(US10647708, Compound 23)
Affinity DataIC50: 1.69E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442017BDBM442017(US10647708, Compound 7)
Affinity DataIC50: 1.94E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442053BDBM442053(US10647708, Compound 42)
Affinity DataIC50: 2.83E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442049BDBM442049(US10647708, Compound 38)
Affinity DataIC50: 2.88E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442018BDBM442018(US10647708, Compound 8)
Affinity DataIC50: 3.09E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442041BDBM442041(US10647708, Compound 30)
Affinity DataIC50: 3.12E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442042BDBM442042(US10647708, Compound 31)
Affinity DataIC50: 3.16E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442043BDBM442043(US10647708, Compound 32)
Affinity DataIC50: 3.54E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442037BDBM442037(US10647708, Compound 26)
Affinity DataIC50: 3.75E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442026BDBM442026(US10647708, Compound 15)
Affinity DataIC50: 3.98E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442020BDBM442020(US10647708, Compound 10)
Affinity DataIC50: 3.98E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442019BDBM442019(US10647708, Compound 9)
Affinity DataIC50: 4.35E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442056BDBM442056(N-(4-(3,4-dihydroisoquinolin-2(1H)-yl)-3-hydroxybu...)
Affinity DataIC50: 5.23E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442052BDBM442052(US10647708, Compound 41)
Affinity DataIC50: 5.29E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442038BDBM442038(US10647708, Compound 27)
Affinity DataIC50: 5.62E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442036BDBM442036(US10647708, Compound 25)
Affinity DataIC50: 6.35E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442033BDBM442033(US10647708, Compound 22)
Affinity DataIC50: 7.02E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442023BDBM442023(US10647708, Compound 13)
Affinity DataIC50: 7.09E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442044BDBM442044(US10647708, Compound 33)
Affinity DataIC50: 7.45E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442029BDBM442029(US10647708, Compound 18)
Affinity DataIC50: 9.79E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442040BDBM442040(US10647708, Compound 29)
Affinity DataIC50: 1.08E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442039BDBM442039(US10647708, Compound 28)
Affinity DataIC50: 1.23E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442027BDBM442027(US10647708, Compound 16)
Affinity DataIC50: 1.30E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442015BDBM442015(US10647708, Compound 6)
Affinity DataIC50: 1.31E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442055BDBM442055(2-Chloro-N-(4-(3,4-dihydroisoquinolin-2(1H)-yl)-3-...)
Affinity DataIC50: 1.37E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442028BDBM442028(US10647708, Compound 17)
Affinity DataIC50: 1.50E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442035BDBM442035(US10647708, Compound 24)
Affinity DataIC50: 2.54E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442021BDBM442021(US10647708, Compound 11)
Affinity DataIC50: 3.92E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442013BDBM442013(US10647708, Compound 4)
Affinity DataIC50: 5.17E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442045BDBM442045(US10647708, Compound 34)
Affinity DataIC50: 5.61E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Ctxt

US Patent
LigandChemical structure of BindingDB Monomer ID 442054BDBM442054(US10647708, Compound 43)
Affinity DataIC50: 1.06E+5nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent