Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 10927
TargetOrexin receptor type 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM579107(2-bromo-2-cyclopropyl acetamide | US11479552, Exam...)
Affinity DataEC50:  0.990nMAssay Description:HEK293 (human embryonic kidney 293) cells with forced expression of human OX1R (hOX1R) or human OX2R (hOX2R) were seeded in a 384-well microplate (Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM579107(2-bromo-2-cyclopropyl acetamide | US11479552, Exam...)
Affinity DataEC50:  2.30nMAssay Description:Human Embryonic Kidney cells 293 (HEK293) cells with forced expression of hOX1R or hOX2R were seeded in a 384-well microplate (Greiner) at 10,000 per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM579108(3-methoxyisonicotinonitrile | US11479552, Example ...)
Affinity DataEC50:  3.08nMAssay Description:HEK293 (human embryonic kidney 293) cells with forced expression of human OX1R (hOX1R) or human OX2R (hOX2R) were seeded in a 384-well microplate (Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM579109((R)-2-((1R,3S,5S)-3-((3S,4R)-1-(5-chloropyrimidin-...)
Affinity DataEC50:  4.30nMAssay Description:Human Embryonic Kidney cells 293 (HEK293) cells with forced expression of hOX1R or hOX2R were seeded in a 384-well microplate (Greiner) at 10,000 per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM579110((R)-2-cyclopropyl-2-((1R,3S,5S)-3-((2S, 4S)-1-(5-f...)
Affinity DataEC50:  4.40nMAssay Description:Human Embryonic Kidney cells 293 (HEK293) cells with forced expression of hOX1R or hOX2R were seeded in a 384-well microplate (Greiner) at 10,000 per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM579108(3-methoxyisonicotinonitrile | US11479552, Example ...)
Affinity DataEC50: >100nMAssay Description:HEK293 (human embryonic kidney 293) cells with forced expression of human OX1R (hOX1R) or human OX2R (hOX2R) were seeded in a 384-well microplate (Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM579107(2-bromo-2-cyclopropyl acetamide | US11479552, Exam...)
Affinity DataEC50: >100nMAssay Description:HEK293 (human embryonic kidney 293) cells with forced expression of human OX1R (hOX1R) or human OX2R (hOX2R) were seeded in a 384-well microplate (Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM579109((R)-2-((1R,3S,5S)-3-((3S,4R)-1-(5-chloropyrimidin-...)
Affinity DataEC50:  1.40E+3nMAssay Description:Human Embryonic Kidney cells 293 (HEK293) cells with forced expression of hOX1R or hOX2R were seeded in a 384-well microplate (Greiner) at 10,000 per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM579110((R)-2-cyclopropyl-2-((1R,3S,5S)-3-((2S, 4S)-1-(5-f...)
Affinity DataEC50:  3.90E+3nMAssay Description:Human Embryonic Kidney cells 293 (HEK293) cells with forced expression of hOX1R or hOX2R were seeded in a 384-well microplate (Greiner) at 10,000 per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM579107(2-bromo-2-cyclopropyl acetamide | US11479552, Exam...)
Affinity DataEC50:  4.70E+3nMAssay Description:Human Embryonic Kidney cells 293 (HEK293) cells with forced expression of hOX1R or hOX2R were seeded in a 384-well microplate (Greiner) at 10,000 per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent