Compile Data Set for Download or QSAR
Report error Found 216 Enz. Inhib. hit(s) with all data for entry = 12761
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726177BDBM726177(US12247004, Compound ANASIA-041-1)
Affinity DataIC50: 17.7nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726265BDBM726265(US12247004, Compound ANASIA-103-1)
Affinity DataIC50: 19.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726297BDBM726297(US12247004, Compound ANASIA-124-1)
Affinity DataIC50: 21.3nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726132BDBM726132(US12247004, Compound ANASIA-011-1)
Affinity DataIC50: 26.2nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726113BDBM726113(US12247004, Compound ANASIA-002-1)
Affinity DataIC50: 27.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726261BDBM726261(US12247004, Compound ANASIA-100-1)
Affinity DataIC50: 27.8nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726251BDBM726251(US12247004, Compound ANASIA-095-1)
Affinity DataIC50: 29nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726126BDBM726126(US12247004, Compound ANASIA-008-1)
Affinity DataIC50: 30.6nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726260BDBM726260(US12247004, Compound ANASIA-100)
Affinity DataIC50: 32.8nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726230BDBM726230(US12247004, Compound ANASIA-081-1)
Affinity DataIC50: 33.9nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726292BDBM726292(US12247004, Compound ANASIA-121-1)
Affinity DataIC50: 41.7nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726206BDBM726206(US12247004, Compound ANASIA-062-1)
Affinity DataIC50: 47.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726247BDBM726247(US12247004, Compound ANASIA-092-1)
Affinity DataIC50: 48.4nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726140BDBM726140(US12247004, Compound ANASIA-015-1)
Affinity DataIC50: 56.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726116BDBM726116(US12247004, Compound ANASIA-003-1)
Affinity DataIC50: 61.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726281BDBM726281(US12247004, Compound ANASIA-114-1)
Affinity DataIC50: 61.8nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726123BDBM726123(US12247004, Compound ANASIA-007-1)
Affinity DataIC50: 63.3nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726183BDBM726183(US12247004, Compound ANASIA-044-1)
Affinity DataIC50: 71nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726317BDBM726317(US12247004, Compound ANASIA-136-1)
Affinity DataIC50: 71.8nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726131BDBM726131(US12247004, Compound ANASIA-011)
Affinity DataIC50: 71.9nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726257BDBM726257(US12247004, Compound ANASIA-099)
Affinity DataIC50: 72.2nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726240BDBM726240(US12247004, Compound ANASIA-088-1)
Affinity DataIC50: 75.3nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726188BDBM726188(US12247004, Compound ANASIA-047-1)
Affinity DataIC50: 76.4nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726138BDBM726138(US12247004, Compound ANASIA-014-1)
Affinity DataIC50: 81.1nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726135BDBM726135(US12247004, Compound ANASIA-012-1)
Affinity DataIC50: 87.4nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726118BDBM726118(US12247004, Compound ANASIA-004)
Affinity DataIC50: 91.6nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726115BDBM726115(US12247004, Compound ANASIA-003)
Affinity DataIC50: 92.9nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726312BDBM726312(US12247004, Compound ANASIA-133-1)
Affinity DataIC50: 97.3nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726219BDBM726219(US12247004, Compound ANASIA-074)
Affinity DataIC50: 99.2nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726288BDBM726288(US12247004, Compound ANASIA-119-1)
Affinity DataIC50: 99.7nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726271BDBM726271(US12247004, Compound ANASIA-107-1)
Affinity DataIC50: 106nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726112BDBM726112(US12247004, Compound ANASIA-002)
Affinity DataIC50: 110nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726181BDBM726181(US12247004, Compound ANASIA-043-1)
Affinity DataIC50: 112nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726258BDBM726258(US12247004, Compound ANASIA-099-1)
Affinity DataIC50: 124nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726273BDBM726273(US12247004, Compound ANASIA-108-1)
Affinity DataIC50: 127nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726154BDBM726154(US12247004, Compound ANASIA-024-1)
Affinity DataIC50: 141nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726213BDBM726213(US12247004, Compound ANASIA-068)
Affinity DataIC50: 141nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726215BDBM726215(US12247004, Compound ANASIA-070)
Affinity DataIC50: 143nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726125BDBM726125(US12247004, Compound ANASIA-008)
Affinity DataIC50: 144nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726145BDBM726145(US12247004, Compound ANASIA-017)
Affinity DataIC50: 145nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726255BDBM726255(US12247004, Compound ANASIA-098-1)
Affinity DataIC50: 148nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726129BDBM726129(US12247004, Compound ANASIA-009-2)
Affinity DataIC50: 149nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726121BDBM726121(US12247004, Compound ANASIA-005-2)
Affinity DataIC50: 151nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726134BDBM726134(US12247004, Compound ANASIA-012)
Affinity DataIC50: 155nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726233BDBM726233(US12247004, Compound ANASIA-083-1)
Affinity DataIC50: 157nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726294BDBM726294(US12247004, Compound ANASIA-122-1)
Affinity DataIC50: 167nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726216BDBM726216(US12247004, Compound ANASIA-071)
Affinity DataIC50: 173nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726304BDBM726304(US12247004, Compound ANASIA-127-2)
Affinity DataIC50: 192nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726242BDBM726242(US12247004, Compound ANASIA-089-1)
Affinity DataIC50: 195nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandChemical structure of BindingDB Monomer ID 726244BDBM726244(US12247004, Compound ANASIA-090)
Affinity DataIC50: 199nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

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