Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 13322
TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779962BDBM779962(Methyl 4-[[6-[2-chloro-3-fluoro-4-(trifluoromethox...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779959BDBM779959(Methyl 4-[[2-fluoro-6-[3-fluoro-2-methyl-4-(triflu...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779958BDBM779958(Methyl 4-[[6-[3-fluoro-2-methyl-4-(trifluoromethox...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779957BDBM779957(Methyl 5-[[2-fluoro-6-[2-methoxy-4-(trifluorometho...)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779972BDBM779972(US12440481, Compound 30)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779956BDBM779956(Methyl 5-[[2-fluoro-6-[3-fluoro-2-methoxy-4-(trifl...)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779953BDBM779953(methyl 5-[[2-fluoro-6-[2-(trideuteriomethoxy)-4-(t...)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779967BDBM779967(Methyl 4-[[2-hydroxy-6-[2-methoxy-4-(trifluorometh...)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779948BDBM779948(methyl 4-[[5-fluoro-2-[2-(trideuteriomethoxy)-4-(t...)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779947BDBM779947(methyl 4-[[2-fluoro-6-[4-(trifluoromethoxy)phenoxy...)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779946BDBM779946(methyl 4-[[3-cyclopropyl-6-[2-methoxy-4-(trifluoro...)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779977BDBM779977(US12440481, Compound 35)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779971BDBM779971(US12440481, Compound 29)
Affinity DataIC50: 750nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779950BDBM779950(methyl 4-[[2-[2-(trideuteriomethoxy)-4-(trifluorom...)
Affinity DataIC50: 750nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779965BDBM779965(Methyl 2-[[2-fluoro-6-[3-fluoro-2-methoxy-4-(trifl...)
Affinity DataIC50: 750nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779960BDBM779960(Methyl 4-[[6-(3,4-difluoro-2-methyl-phenoxy)-2-met...)
Affinity DataIC50: 750nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779955BDBM779955(methyl 5-[[2-fluoro-6-[4-(trifluoromethoxy)phenoxy...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779954BDBM779954(methyl 5-[[2-[2-(trideuteriomethoxy)-4-(trifluorom...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779952BDBM779952(methyl 5-[[2-fluoro-6-(4-fluoro-2-methoxy-phenoxy)...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779951BDBM779951(tert-butyl N-[4-[[2-[2-(trideuteriomethoxy)-4-(tri...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779964BDBM779964(Methyl 4-[[6-[2-chloro-4-(trifluoromethoxy)phenoxy...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779963BDBM779963(Methyl 4-[[2-fluoro-6-[2-methoxy-4-(trifluorometho...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779961BDBM779961(Methyl 4-[[6-(3,4-difluoro-2-methyl-phenoxy)-2-met...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779973BDBM779973(US12440481, Compound 31)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779970BDBM779970(US12440481, Compound 28)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779969BDBM779969(US12440481, Compound 27)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779968BDBM779968(US12440481, Compound 26)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779966BDBM779966(Methyl 2-[[6-[3-fluoro-2-methoxy-4-(trifluorometho...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779949BDBM779949(tert-butyl N-[4-[[5-fluoro-2-[2-(trideuteriomethox...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779945BDBM779945(Methyl 5-[[5-fluoro-2-[2-(trideuteriomethoxy)-4-(t...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779976BDBM779976(US12440481, Compound 34)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779975BDBM779975(US12440481, Compound 33)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 779974BDBM779974(US12440481, Compound 32)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent