Compile Data Set for Download or QSAR
Report error Found 274 Enz. Inhib. hit(s) with all data for entry = 13411
LigandChemical structure of BindingDB Monomer ID 50576738BDBM50576738(CHEMBL4856454 | US12473289, Example 39-27)
Affinity DataIC50: 1.10nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787603BDBM787603(US12473289, Example 41-1)
Affinity DataIC50: 1.20nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787493BDBM787493(Ethyl(4-oxo-3-(1-(2,2,3,3,3-pentafluoropropyl)-1H-...)
Affinity DataIC50: 1.60nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 50576736BDBM50576736(CHEMBL4872983 | US12473289, Example 39-19)
Affinity DataIC50: 1.70nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 50576737BDBM50576737(CHEMBL4855704 | US12473289, Example 39-23)
Affinity DataIC50: 2.10nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 50576735BDBM50576735(CHEMBL4868627 | US12473289, Example 39-17)
Affinity DataIC50: 2.40nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787469BDBM787469(3-(4-(((1R)-2,2-Difluorocyclopropyl)methoxy)phenyl...)
Affinity DataIC50: 2.70nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787377BDBM787377(8-methyl-3-(4-(2,2,2- trifluoroethoxy)phenyl)-2- (...)
Affinity DataIC50: 2.70nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787366BDBM787366(3-(4- (cyclopropylmethoxy)phenyl)- 8-(methyloxy-d3...)
Affinity DataIC50: 3.20nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787319BDBM787319(8-methoxy-3-(4-(2,2,2- trifluoroethoxy)phenyl)-2- ...)
Affinity DataIC50: 3.40nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787351BDBM787351(8-methoxy-3-(4- propylphenyl)-2- (trifluoromethyl)...)
Affinity DataIC50: 3.60nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787559BDBM787559(3-[1-(2,2,3,3,3- pentafluoropropyl)- 1H-pyrazol-4-...)
Affinity DataIC50: 3.70nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787531BDBM787531(7-Chloro-3-[1-(2,2,3,3,3-pentafluoropropyl)-1H-pyr...)
Affinity DataIC50: 3.80nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787430BDBM787430(8-(methyl-d3)-3-(4- (2,2,2- trifluoroethoxy)phenyl...)
Affinity DataIC50: 3.90nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787406BDBM787406(8-Methoxy-3-(4-(2,2,3,3,3-pentafluoropropoxy)pheny...)
Affinity DataIC50: 4nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787358BDBM787358(8-(methyloxy-d3)- 3-(4-(2,2,2- trifluoroethoxy) ph...)
Affinity DataIC50: 4nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787423BDBM787423(8-chloro-3-(4-(2,2,2- trifluoroethoxy)phenyl)- 2-(...)
Affinity DataIC50: 4.10nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787609BDBM787609(7-fluoro-8- methoxy-3-[4- (2,2,2- trifluoroethoxy)...)
Affinity DataIC50: 4.10nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787594BDBM787594(3-{1-[(3,3- difluorocyclobutyl) methyl]-1H- pyrazo...)
Affinity DataIC50: 4.60nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787611BDBM787611(3-{1-[(2,2- difluorocyclopropyl) methyl]-1H- pyraz...)
Affinity DataIC50: 5nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787361BDBM787361(3-(4-(cyclopropyl- methoxy)phenyl)-8- methoxy-2- (...)
Affinity DataIC50: 5.10nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787331BDBM787331(3-(3-fluoro-4-(2,2,2- trifluoroethoxy)phenyl)-8- m...)
Affinity DataIC50: 5.10nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787466BDBM787466(4-oxo-3-(4-(2,2,2- trifluoroethoxy) phenyl)-2- (tr...)
Affinity DataIC50: 5.20nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787330BDBM787330(8-methoxy-3-(1-phenyl-1H- pyrazol-4-yl)-2- (triflu...)
Affinity DataIC50: 5.40nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787332BDBM787332(8-methoxy-3-(4- (trifluoromethoxy)phenyl)-2- (trif...)
Affinity DataIC50: 5.40nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787392BDBM787392(3-(4-(2,2- difluoroethoxy)phenyl)-8- (methyloxy-d3...)
Affinity DataIC50: 5.60nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787433BDBM787433(8-(hydroxymethyl)-3-(4- (2,2,2- trifluoroethoxy)ph...)
Affinity DataIC50: 5.60nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787468BDBM787468(3-(4-(((1R)-2,2-Difluorocyclopropyl)methoxy)phenyl...)
Affinity DataIC50: 5.70nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787398BDBM787398((4-(8-Methoxy-4-oxo-2-(trifluoromethyl)-4H-pyrido[...)
Affinity DataIC50: 5.80nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787396BDBM787396(3-(2-fluoro-4- (trifluoromethoxy)phenyl)- 8-methox...)
Affinity DataIC50: 5.90nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787538BDBM787538(8-methoxy-3-[1- (2,2,3,3,3- pentafluoropropyl)- 1H...)
Affinity DataIC50: 6.30nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787467BDBM787467(8-acetyl-3-(4-(2,2,2- trifluoroethoxy)phenyl)-2- (...)
Affinity DataIC50: 6.40nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787353BDBM787353(2-ethyl-8-methoxy-3-(4- (2,2,2- trifluoroethoxy)ph...)
Affinity DataIC50: 6.60nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787438BDBM787438(3-(4-((2,2-difluorocyclo- propyl)methoxy)phenyl)- ...)
Affinity DataIC50: 6.60nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787390BDBM787390(3-(4- (difluoromethoxy)phenyl)-8- methoxy-2-(trifl...)
Affinity DataIC50: 6.60nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787451BDBM787451(8-amino-3-(4- (2,2,2- trifluoroeth- oxy)phenyl)-2-...)
Affinity DataIC50: 6.80nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787539BDBM787539(8-methoxy-2- (trifluoromethyl)- 3-[1-(3,3,3- trifl...)
Affinity DataIC50: 6.90nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787452BDBM787452(8-(methylamino)-3-(4- (2,2,2- trifluoroethoxy)phen...)
Affinity DataIC50: 7nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787389BDBM787389(3-(4-(2,2- difluoroethoxy)phenyl)-8- methoxy-2- (t...)
Affinity DataIC50: 7.90nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787494BDBM787494(8-chloro-3-(1- (2,2,3,3,3- pentafluoropropyl)- 1H-...)
Affinity DataIC50: 8.20nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787391BDBM787391(3-(2-fluoro-4-(2,2,2- trifluoroethoxy)phenyl)-8- m...)
Affinity DataIC50: 8.5nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787543BDBM787543(8-Methoxy-2-(trifluoromethyl)-3-[3-(3,3,3-trifluor...)
Affinity DataIC50: 8.70nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787341BDBM787341(3-(2-fluoro-4-(2,2,2- trifluoroethoxy)phenyl)- 8-m...)
Affinity DataIC50: 8.90nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787528BDBM787528(3-[1-(2,2,3,3,3- pentafluoropropyl)- 1H-pyrazol-4-...)
Affinity DataIC50: 8.90nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787437BDBM787437(8-(fluoromethyl)-3-(4- (2,2,2- trifluoroethoxy)phe...)
Affinity DataIC50: 9.40nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787369BDBM787369(2-(difluoromethyl)- 3-(3-fluoro-4-(2,2,2- trifluor...)
Affinity DataIC50: 9.90nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787496BDBM787496(8-(Fluoromethoxy)-3-[1-(2,2,3,3,3-pentafluoropropy...)
Affinity DataIC50: 10.1nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787317BDBM787317(3-(4-(2,2,2- trifluoroethoxy)phenyl)-2- (trifluoro...)
Affinity DataIC50: 10.4nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787425BDBM787425(8-(methylsulfanyl)-3-(4- (2,2,2- trifluoroethoxy)p...)
Affinity DataIC50: 10.4nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 787587BDBM787587(3-(1-{[(1S)-2,2-Difluorocyclopropyl]methyl}-1H-pyr...)
Affinity DataIC50: 10.5nMAssay Description:Membrane preparations of D5D-overexpressing HEK293 6E cells were prepared in which the total protein concentration was 5.6 mg/mL. Stock D5D membrane ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/8/2026
Entry Details

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