Compile Data Set for Download or QSAR
Report error Found 1049 Enz. Inhib. hit(s) with all data for entry = 11465
TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 617829BDBM617829(US20230286970, Compound 1 | US20230286970, Compoun...)
Affinity DataIC50: 7nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618082BDBM618082(US20230286970, Compound 25)
Affinity DataIC50: 7nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618080BDBM618080(US20230286970, Compound 24)
Affinity DataIC50: 7nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618068BDBM618068(US20230286970, Compound 18 | 6-(1-((5-(5-(difluoro...)
Affinity DataIC50: 8nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618084BDBM618084(US20230286970, Compound 26)
Affinity DataIC50: 8nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618066BDBM618066(US20230286970, Compound 17 | 5-(1-((5-(5-(difluoro...)
Affinity DataIC50: 8nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618086BDBM618086(US20230286970, Compound 27 | 7'-(2-((5-(5-(difluor...)
Affinity DataIC50: 9nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618327BDBM618327(US20230286970, Compound 361)
Affinity DataIC50: 9nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 617829BDBM617829(US20230286970, Compound 1 | US20230286970, Compoun...)
Affinity DataIC50: 9nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618157BDBM618157(US20230286970, Compound 276)
Affinity DataIC50: 9nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 617942BDBM617942(US20230286970, Compound 3)
Affinity DataIC50: 10nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 617923BDBM617923(US20230286970, Compound 2)
Affinity DataIC50: 10nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618093BDBM618093(US20230286970, Compound 30)
Affinity DataIC50: 10nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618091BDBM618091(US20230286970, Compound 29)
Affinity DataIC50: 10nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618070BDBM618070(US20230286970, Compound 19)
Affinity DataIC50: 11nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618088BDBM618088(US20230286970, Compound 28 | US20230286970, Compou...)
Affinity DataIC50: 11nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618072BDBM618072(US20230286970, Compound 20)
Affinity DataIC50: 11nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618219BDBM618219(US20230286970, Compound 307)
Affinity DataIC50: 11nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618323BDBM618323(US20230286970, Compound 359)
Affinity DataIC50: 11nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618385BDBM618385(US20230286970, Compound 387)
Affinity DataIC50: 12nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618377BDBM618377(US20230286970, Compound 420 | N-(4-(5-(4-(5-(diflu...)
Affinity DataIC50: 12nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618319BDBM618319(US20230286970, Compound 357)
Affinity DataIC50: 12nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 617987BDBM617987(US20230286970, Compound 5 | 5-(1-((5-(5-(difluorom...)
Affinity DataIC50: 12nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 617985BDBM617985(US20230286970, Compound 4)
Affinity DataIC50: 12nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618046BDBM618046(US20230286970, Compound 7 | 5-(2-((5-(5-(difluorom...)
Affinity DataIC50: 13nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618078BDBM618078(US20230286970, Compound 23)
Affinity DataIC50: 13nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618044BDBM618044(US20230286970, Compound 6 | US20230286970, Compoun...)
Affinity DataIC50: 13nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618088BDBM618088(US20230286970, Compound 28 | US20230286970, Compou...)
Affinity DataIC50: 13nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618371BDBM618371(US20230286970, Compound 383)
Affinity DataIC50: 13nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618095BDBM618095(US20230286970, Compound 31)
Affinity DataIC50: 14nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618099BDBM618099(US20230286970, Compound 33)
Affinity DataIC50: 14nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618261BDBM618261(US20230286970, Compound 328)
Affinity DataIC50: 14nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618048BDBM618048(US20230286970, Compound 8)
Affinity DataIC50: 14nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618097BDBM618097(US20230286970, Compound 32 | (R)-5-(1-(1-(5-(5-(di...)
Affinity DataIC50: 14nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618101BDBM618101(US20230286970, Compound 34)
Affinity DataIC50: 15nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618143BDBM618143(US20230286970, Compound 269 | N-(4-(1-(4-(5-(diflu...)
Affinity DataIC50: 15nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618050BDBM618050(US20230286970, Compound 9)
Affinity DataIC50: 15nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618221BDBM618221(US20230286970, Compound 308 | 5-[1-[[5-[5-(difluor...)
Affinity DataIC50: 15nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618103BDBM618103(US20230286970, Compound 35)
Affinity DataIC50: 16nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618052BDBM618052(US20230286970, Compound 10 | N-(4-(1-(4-(5-(difluo...)
Affinity DataIC50: 16nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618105BDBM618105(US20230286970, Compound 36 | 7'-(1-((5-(5-(difluor...)
Affinity DataIC50: 16nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618249BDBM618249(US20230286970, Compound 322)
Affinity DataIC50: 17nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618361BDBM618361(US20230286970, Compound 378)
Affinity DataIC50: 17nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618076BDBM618076(US20230286970, Compound 22 | N-(4-(1-(4-(5-(difluo...)
Affinity DataIC50: 17nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618044BDBM618044(US20230286970, Compound 6 | US20230286970, Compoun...)
Affinity DataIC50: 17nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618074BDBM618074(US20230286970, Compound 21 | US20230286970, Compou...)
Affinity DataIC50: 17nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618107BDBM618107(US20230286970, Compound 37)
Affinity DataIC50: 17nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618076BDBM618076(US20230286970, Compound 22 | N-(4-(1-(4-(5-(difluo...)
Affinity DataIC50: 17nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618363BDBM618363(US20230286970, Compound 379)
Affinity DataIC50: 17nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandChemical structure of BindingDB Monomer ID 618111BDBM618111(US20230286970, Compound 39 | US20230286970, Compou...)
Affinity DataIC50: 18nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

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