Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 11941
TargetTyrosine-protein kinase JAK1(Human)
The National Institutes Of Pharmaceutical R&D Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 663045BDBM663045(US20240109890, Compound 1)
Affinity DataIC50: 50nMAssay Description:Experimental materials: JAK1 kinase (Invitrogen, PV4744), ATP (Promega, V915B), ADP-Glo Kinase Assay (Promega, V9101), IRS1 (Signalchem, 140-58-1000)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
The National Institutes Of Pharmaceutical R&D Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 663047BDBM663047(US20240109890, Compound 1-b)
Affinity DataIC50: 50nMAssay Description:Experimental materials: JAK1 kinase (Invitrogen, PV4744), ATP (Promega, V915B), ADP-Glo Kinase Assay (Promega, V9101), IRS1 (Signalchem, 140-58-1000)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
The National Institutes Of Pharmaceutical R&D Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 663046BDBM663046(US20240109890, Compound 1-a)
Affinity DataIC50: 50nMAssay Description:Experimental materials: JAK1 kinase (Invitrogen, PV4744), ATP (Promega, V915B), ADP-Glo Kinase Assay (Promega, V9101), IRS1 (Signalchem, 140-58-1000)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
The National Institutes Of Pharmaceutical R&D Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 663050BDBM663050(US20240109890, Compound 2-b)
Affinity DataIC50: 200nMAssay Description:Experimental materials: JAK1 kinase (Invitrogen, PV4744), ATP (Promega, V915B), ADP-Glo Kinase Assay (Promega, V9101), IRS1 (Signalchem, 140-58-1000)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
The National Institutes Of Pharmaceutical R&D Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 663049BDBM663049(US20240109890, Compound 2-a)
Affinity DataIC50: 650nMAssay Description:Experimental materials: JAK1 kinase (Invitrogen, PV4744), ATP (Promega, V915B), ADP-Glo Kinase Assay (Promega, V9101), IRS1 (Signalchem, 140-58-1000)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
The National Institutes Of Pharmaceutical R&D Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 663048BDBM663048(US20240109890, Compound 2)
Affinity DataIC50: 650nMAssay Description:Experimental materials: JAK1 kinase (Invitrogen, PV4744), ATP (Promega, V915B), ADP-Glo Kinase Assay (Promega, V9101), IRS1 (Signalchem, 140-58-1000)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2024
Entry Details
US Patent