Compile Data Set for Download or QSAR
Report error Found 370 Enz. Inhib. hit(s) with all data for entry = 12069
TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496842BDBM496842(SARS-CoV-2 PLpro Inhibitor, 72 | US20240166598, Co...)
Affinity DataKd:  110nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496864BDBM496864(SARS-CoV-2 PLpro Inhibitor, 94 | US20240166598, Ex...)
Affinity DataIC50: 110nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 676274BDBM676274(US20240166598, Compound XR8-89)
Affinity DataIC50: 113nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 676274BDBM676274(US20240166598, Compound XR8-89)
Affinity DataKd:  113nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496858BDBM496858(SARS-CoV-2 PLpro Inhibitor, 88 | US20240166598, Co...)
Affinity DataIC50: 170nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496858BDBM496858(SARS-CoV-2 PLpro Inhibitor, 88 | US20240166598, Co...)
Affinity DataIC50: 170nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496862BDBM496862(SARS-CoV-2 PLpro Inhibitor, 92 | US20240166598, Ex...)
Affinity DataIC50: 210nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 676272BDBM676272(US20240166598, Compound XR8-83)
Affinity DataIC50: 210nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496842BDBM496842(SARS-CoV-2 PLpro Inhibitor, 72 | US20240166598, Co...)
Affinity DataKd:  235nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496865BDBM496865(SARS-CoV-2 PLpro Inhibitor, 95 | US20240166598, Ex...)
Affinity DataIC50: 250nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 676275BDBM676275(US20240166598, Compound XR8-96)
Affinity DataIC50: 250nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496843BDBM496843(SARS-CoV-2 PLpro Inhibitor, 73 | US20240166598, Co...)
Affinity DataKd:  300nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496856BDBM496856(SARS-CoV-2 PLpro Inhibitor, 86 | US20240166598, Ex...)
Affinity DataIC50: 330nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 676266BDBM676266(US20240166598, Compound XR8-65 | US20240166598, Co...)
Affinity DataIC50: 330nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496859BDBM496859(SARS-CoV-2 PLpro Inhibitor, 89 | US20240166598, Co...)
Affinity DataIC50: 370nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496859BDBM496859(SARS-CoV-2 PLpro Inhibitor, 89 | US20240166598, Co...)
Affinity DataIC50: 370nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496843BDBM496843(SARS-CoV-2 PLpro Inhibitor, 73 | US20240166598, Co...)
Affinity DataKd:  372nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496842BDBM496842(SARS-CoV-2 PLpro Inhibitor, 72 | US20240166598, Co...)
Affinity DataIC50: 380nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496842BDBM496842(SARS-CoV-2 PLpro Inhibitor, 72 | US20240166598, Co...)
Affinity DataIC50: 390nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496865BDBM496865(SARS-CoV-2 PLpro Inhibitor, 95 | US20240166598, Ex...)
Affinity DataKd:  400nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 676275BDBM676275(US20240166598, Compound XR8-96)
Affinity DataKd:  400nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496861BDBM496861(SARS-CoV-2 PLpro Inhibitor, 91 | US20240166598, Co...)
Affinity DataIC50: 410nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496861BDBM496861(SARS-CoV-2 PLpro Inhibitor, 91 | US20240166598, Co...)
Affinity DataIC50: 410nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496840BDBM496840(SARS-CoV-2 PLpro Inhibitor, 70 | US20240166598, Co...)
Affinity DataKd:  430nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496840BDBM496840(SARS-CoV-2 PLpro Inhibitor, 70 | US20240166598, Co...)
Affinity DataKd:  430nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496864BDBM496864(SARS-CoV-2 PLpro Inhibitor, 94 | US20240166598, Ex...)
Affinity DataKd:  430nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496863BDBM496863(SARS-CoV-2 PLpro Inhibitor, 93 | US20240166598, Ex...)
Affinity DataIC50: 430nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 676273BDBM676273(US20240166598, Compound XR8-84)
Affinity DataIC50: 430nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496843BDBM496843(SARS-CoV-2 PLpro Inhibitor, 73 | US20240166598, Co...)
Affinity DataIC50: 530nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496863BDBM496863(SARS-CoV-2 PLpro Inhibitor, 93 | US20240166598, Ex...)
Affinity DataKd:  530nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 676273BDBM676273(US20240166598, Compound XR8-84)
Affinity DataKd:  530nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496843BDBM496843(SARS-CoV-2 PLpro Inhibitor, 73 | US20240166598, Co...)
Affinity DataIC50: 560nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496835BDBM496835(SARS-CoV-2 PLpro Inhibitor, 65 | US20240166598, Co...)
Affinity DataIC50: 590nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496522BDBM496522(SARS-CoV-2 PLpro Inhibitor, 6 | US20240166598, Com...)
Affinity DataIC50: 600nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 676179BDBM676179(5-(azetidin-3-yloxy)-N- ((R)-1-(3-(5-((((1S,3R)-3-...)
Affinity DataIC50: 600nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496522BDBM496522(SARS-CoV-2 PLpro Inhibitor, 6 | US20240166598, Com...)
Affinity DataIC50: 600nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 676181BDBM676181((1R,3S)-3-(((5-(3-((R)-1- (5-(azetidin-3-ylamino)-...)
Affinity DataIC50: 600nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496857BDBM496857(SARS-CoV-2 PLpro Inhibitor, 87 | US20240166598, Ex...)
Affinity DataIC50: 620nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 676266BDBM676266(US20240166598, Compound XR8-65 | US20240166598, Co...)
Affinity DataIC50: 620nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496862BDBM496862(SARS-CoV-2 PLpro Inhibitor, 92 | US20240166598, Ex...)
Affinity DataKd:  630nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 676272BDBM676272(US20240166598, Compound XR8-83)
Affinity DataKd:  630nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496860BDBM496860(SARS-CoV-2 PLpro Inhibitor, 90 | US20240166598, Co...)
Affinity DataIC50: 640nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496860BDBM496860(SARS-CoV-2 PLpro Inhibitor, 90 | US20240166598, Co...)
Affinity DataIC50: 640nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496851BDBM496851(SARS-CoV-2 PLpro Inhibitor, 81 | US20240166598, Co...)
Affinity DataIC50: 640nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496851BDBM496851(SARS-CoV-2 PLpro Inhibitor, 81 | US20240166598, Co...)
Affinity DataIC50: 640nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496835BDBM496835(SARS-CoV-2 PLpro Inhibitor, 65 | US20240166598, Co...)
Affinity DataIC50: 650nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496854BDBM496854(SARS-CoV-2 PLpro Inhibitor, 84 | US20240166598, Co...)
Affinity DataKd:  668nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496854BDBM496854(SARS-CoV-2 PLpro Inhibitor, 84 | US20240166598, Co...)
Affinity DataKd:  670nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a [1564-1878](Severe acute respiratory syndrome coronavirus (SAR...)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496555BDBM496555(SARS-CoV-2 PLpro Inhibitor, 9 | US20240166598, Com...)
Affinity DataIC50: 700nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 pg/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
University of Arizona

US Patent
LigandChemical structure of BindingDB Monomer ID 496555BDBM496555(SARS-CoV-2 PLpro Inhibitor, 9 | US20240166598, Com...)
Affinity DataIC50: 700nMAssay Description:The PLpro primary assay using PLpro as prepared above was conducted as described below and provided the data described in Table 7 in the column: Enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

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