Compile Data Set for Download or QSAR
Report error Found 62 Enz. Inhib. hit(s) with all data for entry = 12491
TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706447BDBM706447(7-(4-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [4...)
Affinity DataKi:  10nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 50019951BDBM50019951(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  10nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 10755BDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  20nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706430BDBM706430(6,6a,7,8,9,10-Hexahydropyrazino[1,2-a]Thieno [4,3,...)
Affinity DataKi:  20nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706454BDBM706454(2-(4-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [4...)
Affinity DataKi:  30nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706448BDBM706448(US20240383913, Compound I-20)
Affinity DataKi:  30nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706458BDBM706458(N-(4-(2-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno...)
Affinity DataKi:  80nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706455BDBM706455(1,1-Dimethyl-3-(4-(2-(6a, 7,9,10-Tetrahydropyrazin...)
Affinity DataKi:  80nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706454BDBM706454(2-(4-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [4...)
Affinity DataKi:  90nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706453BDBM706453(2-(4-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [4...)
Affinity DataKi:  100nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706457BDBM706457(US20240383913, Compound (-)-I-27)
Affinity DataKi:  120nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706451BDBM706451(5,6-Dimethoxy-2-(4-(6a,7,9,10-Tetrahydropyrazino[1...)
Affinity DataKi:  160nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706446BDBM706446(7-(3-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [4...)
Affinity DataKi:  160nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706459BDBM706459(N-(4-(2-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno...)
Affinity DataKi:  180nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706455BDBM706455(1,1-Dimethyl-3-(4-(2-(6a, 7,9,10-Tetrahydropyrazin...)
Affinity DataKi:  210nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706452BDBM706452(US20240383913, Compound I-24)
Affinity DataKi:  230nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706446BDBM706446(7-(3-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [4...)
Affinity DataKi:  270nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706445BDBM706445(7-(3-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [4...)
Affinity DataKi:  290nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706453BDBM706453(2-(4-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [4...)
Affinity DataKi:  300nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706436BDBM706436(8-([1, l'-Biphenyl]-3-Ylmethyl)-6,6a, 7,8,9, 10-He...)
Affinity DataKi:  310nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706440BDBM706440(1-(4-Fluorophenyl)-4-(6a,7,9,10-Tetrahydropyrazino...)
Affinity DataKi:  320nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706433BDBM706433(8-(Cyclopropylmethyl)-6,6a,7,8,9,10-Hexahydropyraz...)
Affinity DataKi:  320nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706431BDBM706431(8-Propyl-6,6a,7,8,9,10-Hexahydropyrazino[1,2-a]Thi...)
Affinity DataKi:  380nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706437BDBM706437(8-((5-(4-Fluorophenyl)Pyridin-3-Yl)Methyl)-6,6a,7,...)
Affinity DataKi:  440nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706459BDBM706459(N-(4-(2-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno...)
Affinity DataKi:  450nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706456BDBM706456(US20240383913, Compound (+)-I-27)
Affinity DataKi:  450nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706440BDBM706440(1-(4-Fluorophenyl)-4-(6a,7,9,10-Tetrahydropyrazino...)
Affinity DataKi:  470nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706450BDBM706450(2-(4-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [4...)
Affinity DataKi:  490nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706458BDBM706458(N-(4-(2-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno...)
Affinity DataKi:  520nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706452BDBM706452(US20240383913, Compound I-24)
Affinity DataKi:  630nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706448BDBM706448(US20240383913, Compound I-20)
Affinity DataKi:  640nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706438BDBM706438(1-(3-((6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [...)
Affinity DataKi:  690nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706431BDBM706431(8-Propyl-6,6a,7,8,9,10-Hexahydropyrazino[1,2-a]Thi...)
Affinity DataKi:  710nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706451BDBM706451(5,6-Dimethoxy-2-(4-(6a,7,9,10-Tetrahydropyrazino[1...)
Affinity DataKi:  750nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706445BDBM706445(7-(3-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [4...)
Affinity DataKi:  750nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706438BDBM706438(1-(3-((6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [...)
Affinity DataKi:  800nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706436BDBM706436(8-([1, l'-Biphenyl]-3-Ylmethyl)-6,6a, 7,8,9, 10-He...)
Affinity DataKi:  910nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706434BDBM706434(8-(4-Fluorophenylethyl)-6,6a,7,8,9,10-Hexahydropyr...)
Affinity DataKi:  920nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706442BDBM706442(N-(2-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [4...)
Affinity DataKi:  1.19E+3nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706450BDBM706450(2-(4-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [4...)
Affinity DataKi:  1.20E+3nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706441BDBM706441(4-Fluoro-N-(2-(6a,7,9,10-Tetrahydropyrazino[1,2-a]...)
Affinity DataKi:  1.21E+3nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706447BDBM706447(7-(4-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [4...)
Affinity DataKi:  1.41E+3nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706437BDBM706437(8-((5-(4-Fluorophenyl)Pyridin-3-Yl)Methyl)-6,6a,7,...)
Affinity DataKi:  1.46E+3nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706439BDBM706439(1-(4-Fluorophenyl)-2-(6a,7,9,10-Tetrahydropyrazino...)
Affinity DataKi:  1.49E+3nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706441BDBM706441(4-Fluoro-N-(2-(6a,7,9,10-Tetrahydropyrazino[1,2-a]...)
Affinity DataKi:  1.52E+3nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706444BDBM706444(8-(3-(Benzo[d][1,3]Dioxol-5-Yloxy) Propyl)-6,6a, 7...)
Affinity DataKi:  1.55E+3nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706443BDBM706443(8-(2-Phenoxyethyl)-6,6a,7,8,9,10-Hexahydropyrazino...)
Affinity DataKi:  1.71E+3nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706439BDBM706439(1-(4-Fluorophenyl)-2-(6a,7,9,10-Tetrahydropyrazino...)
Affinity DataKi:  2.06E+3nMAssay Description:The affinity of the compounds of the present disclosure for the dopamine D2 receptors was determined by the method of radioligand competition experim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706457BDBM706457(US20240383913, Compound (-)-I-27)
Affinity DataKi:  2.29E+3nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Chinese Academy of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 706432BDBM706432(2-(6a,7,9,10-Tetrahydropyrazino[1,2-a]Thieno [4,3,...)
Affinity DataKi:  4.13E+3nMAssay Description:The affinity of the compounds of the present disclosure for the 5-HT2A receptors was determined by the method of radioligand competition experiment. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
US Patent

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