Compile Data Set for Download or QSAR
Report error Found 94 Enz. Inhib. hit(s) with all data for entry = 13352
TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783192BDBM783192(US20250326769, Example 76)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 783191BDBM783191(US20250326769, Example 66)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783191BDBM783191(US20250326769, Example 66)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783190BDBM783190(US20250326769, Example 58)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783157BDBM783157(US20250326769, Example 8)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 783157BDBM783157(US20250326769, Example 8)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783157BDBM783157(US20250326769, Example 8)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783156BDBM783156((Method C) | US20250326769, Example 7)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783156BDBM783156((Method C) | US20250326769, Example 7)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 783156BDBM783156((Method C) | US20250326769, Example 7)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783156BDBM783156((Method C) | US20250326769, Example 7)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783160BDBM783160(US20250326769, Example 11)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783159BDBM783159(US20250326769, Example 10)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783158BDBM783158(US20250326769, Example 9)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 783158BDBM783158(US20250326769, Example 9)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783158BDBM783158(US20250326769, Example 9)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783155BDBM783155(US20250326769, Example 6)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783154BDBM783154((Method B) | US20250326769, Example 5)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783154BDBM783154((Method B) | US20250326769, Example 5)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 783153BDBM783153(US20250326769, Example 4)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783153BDBM783153(US20250326769, Example 4)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783152BDBM783152(US20250326769, Example 3)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783171BDBM783171(US20250326769, Example 31)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783170BDBM783170(US20250326769, Example 30)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783169BDBM783169(US20250326769, Example 27)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783169BDBM783169(US20250326769, Example 27)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 783169BDBM783169(US20250326769, Example 27)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783169BDBM783169(US20250326769, Example 27)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783175BDBM783175(US20250326769, Example 35)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783174BDBM783174(US20250326769, Example 34)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783173BDBM783173(US20250326769, Example 33)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783172BDBM783172(US20250326769, Example 32)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783163BDBM783163(US20250326769, Example 14)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783163BDBM783163(US20250326769, Example 14)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783162BDBM783162(US20250326769, Example 13)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783161BDBM783161(US20250326769, Example 12)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783168BDBM783168(US20250326769, Example 20)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783167BDBM783167(US20250326769, Example 19)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783167BDBM783167(US20250326769, Example 19)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783166BDBM783166(US20250326769, Example 18)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783165BDBM783165(US20250326769, Example 17)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783187BDBM783187((Method D) | US20250326769, Example 49)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783185BDBM783185(US20250326769, Example 45)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783184BDBM783184(US20250326769, Example 44)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783183BDBM783183(US20250326769, Example 43)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 783190BDBM783190(US20250326769, Example 58)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783190BDBM783190(US20250326769, Example 58)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783188BDBM783188(US20250326769, Example 55)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783187BDBM783187((Method D) | US20250326769, Example 49)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [I1171N,D1203N](Homo sapiens (Human))
Nuvalent

US Patent
LigandChemical structure of BindingDB Monomer ID 783179BDBM783179((Method H) | US20250326769, Example 39)
Affinity DataKi: <50nMAssay Description:First, 250 nL of compound dissolved in DMSO (100-fold of the desired concentration) was dispensed into a 384-well plate. A 12.5 μL substrate solution...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

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