Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 13359
TargetNon-receptor tyrosine-protein kinase TYK2 [556-871](Human)
Zhejiang Wenda Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM783669(US20250333393, Compound 4S)
Affinity DataIC50: 0.290nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [583-855](Human)
Zhejiang Wenda Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM783669(US20250333393, Compound 4S)
Affinity DataIC50: 22nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [808-1132](Human)
Zhejiang Wenda Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM783669(US20250333393, Compound 4S)
Affinity DataIC50: 5.42E+3nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [811-1124](Human)
Zhejiang Wenda Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM783669(US20250333393, Compound 4S)
Affinity DataIC50: 9.90E+3nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [866-1154](Human)
Zhejiang Wenda Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM783669(US20250333393, Compound 4S)
Affinity DataIC50: 9.90E+3nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/19/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [886-1187](Human)
Zhejiang Wenda Pharmaceutical Technology Co.

US Patent
LigandPNGBDBM783669(US20250333393, Compound 4S)
Affinity DataIC50: 9.90E+3nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/19/2026
Entry Details
US Patent