Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 5881
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 98538BDBM98538(US8492392, T-1)
Affinity DataKi:  0.430nM ΔG°:  -53.5kJ/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 98540BDBM98540(US8492392, 1-11)
Affinity DataKi:  0.600nM ΔG°:  -52.6kJ/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50398012BDBM50398012(CHEMBL2180422 | US8492392, 1-17)
Affinity DataKi:  0.630nM ΔG°:  -52.5kJ/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 98545BDBM98545(US8492392, 1-20)
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 98541BDBM98541(US8492392, 1-13)
Affinity DataKi:  0.840nM ΔG°:  -51.8kJ/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50398013BDBM50398013(CHEMBL2180421 | US8492392, K-2)
Affinity DataKi:  0.900nM ΔG°:  -51.6kJ/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 98535BDBM98535(US8492392, P-5)
Affinity DataKi:  0.920nM ΔG°:  -51.6kJ/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50398011BDBM50398011(CHEMBL2180423 | US8492392, O-2)
Affinity DataKi:  0.930nM ΔG°:  -51.5kJ/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50401294BDBM50401294(CHEMBL2204538 | US8492392, Q-2)
Affinity DataKi:  0.990nM ΔG°:  -51.4kJ/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 98544BDBM98544(CHEMBL2204537 | US8492392, 1-19)
Affinity DataKi:  4.55nM ΔG°:  -47.6kJ/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 98539BDBM98539(US8492392, 1-8)
Affinity DataKi:  9.20nM ΔG°:  -45.9kJ/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 98542BDBM98542(US8492392, 1-14)
Affinity DataKi:  9.90nM ΔG°:  -45.7kJ/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 98536BDBM98536(US8492392, R-1)
Affinity DataKi:  12.5nM ΔG°:  -45.1kJ/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50401302BDBM50401302(CHEMBL2205203 | US8492392, 1-7)
Affinity DataKi:  14nM ΔG°:  -44.8kJ/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 98543BDBM98543(US8492392, 1-18)
Affinity DataKi:  15.9nM ΔG°:  -44.5kJ/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 98537BDBM98537(US8492392, S-1)
Affinity DataKi:  16.8nM ΔG°:  -44.4kJ/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 98534BDBM98534(US8492392, N-5)
Affinity DataKi:  31.4nM ΔG°:  -42.8kJ/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
US Patent