Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 212
LigandChemical structure of BindingDB Monomer ID 228154BDBM228154((S)-5-(4-morpholino-5a,6,8,9-tetrahydro-5H- pyrimi...)
Affinity DataKi:  8nM IC50: 76nMAssay Description:N-terminally His-tagged PI3K alpha (Cat. No. PV4789; 0.49 mg/ml), Alexa Fluor 647 labeled kinase Tracer 314 (Cat. No. PV6087), Biotin anti-His Tag an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 228156BDBM228156((R)-5-(2-morpholino-5a,6,8,9-tetrahydro-5H- pyrimi...)
Affinity DataKi:  23nM IC50: 231nMAssay Description:N-terminally His-tagged PI3K alpha (Cat. No. PV4789; 0.49 mg/ml), Alexa Fluor 647 labeled kinase Tracer 314 (Cat. No. PV6087), Biotin anti-His Tag an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 228152BDBM228152((R)-5-(4-morpholino-5a,6,8,9-tetrahydro-5H- pyrimi...)
Affinity DataKi:  42nM IC50: 411nMAssay Description:N-terminally His-tagged PI3K alpha (Cat. No. PV4789; 0.49 mg/ml), Alexa Fluor 647 labeled kinase Tracer 314 (Cat. No. PV6087), Biotin anti-His Tag an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 228153BDBM228153((S)-5-(4-morpholino-5a,6,8,9-tetrahydro-5H- pyrimi...)
Affinity DataIC50: 98.1nMAssay Description:N-terminally His-tagged PI3K alpha (Cat. No. PV4789; 0.49 mg/ml), Alexa Fluor 647 labeled kinase Tracer 314 (Cat. No. PV6087), Biotin anti-His Tag an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 228158BDBM228158((S)-5-(2-morpholino-5a,6,8,9-tetrahydro-5H- pyrimi...)
Affinity DataKi:  166nM IC50: 1.64E+3nMAssay Description:N-terminally His-tagged PI3K alpha (Cat. No. PV4789; 0.49 mg/ml), Alexa Fluor 647 labeled kinase Tracer 314 (Cat. No. PV6087), Biotin anti-His Tag an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 228157BDBM228157((S)-5-(2-morpholino-5a,6,8,9-tetrahydro-5H- pyrimi...)
Affinity DataIC50: 383nMAssay Description:N-terminally His-tagged PI3K alpha (Cat. No. PV4789; 0.49 mg/ml), Alexa Fluor 647 labeled kinase Tracer 314 (Cat. No. PV6087), Biotin anti-His Tag an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 228130BDBM228130((R)-5-(4-morpholino-5a,6,8,9-tetrahydro-5H- pyrimi...)
Affinity DataIC50: 390nMAssay Description:N-terminally His-tagged PI3K alpha (Cat. No. PV4789; 0.49 mg/ml), Alexa Fluor 647 labeled kinase Tracer 314 (Cat. No. PV6087), Biotin anti-His Tag an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 228155BDBM228155((R)-5-(2-morpholino-5a,6,8,9-tetrahydro-5H- pyrimi...)
Affinity DataIC50: 2.62E+3nMAssay Description:N-terminally His-tagged PI3K alpha (Cat. No. PV4789; 0.49 mg/ml), Alexa Fluor 647 labeled kinase Tracer 314 (Cat. No. PV6087), Biotin anti-His Tag an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2018
Entry Details
US Patent