Compile Data Set for Download or QSAR
Report error Found 73 Enz. Inhib. hit(s) with all data for entry = 3283
TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396352BDBM396352(US9980929, Example 54)
Affinity DataIC50: 0.976nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396353BDBM396353(US9980929, Example 55)
Affinity DataIC50: 1.18nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396373BDBM396373(US9980929, Example 75)
Affinity DataIC50: 2.88nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396359BDBM396359(US9980929, Example 61)
Affinity DataIC50: 3.31nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396372BDBM396372(US9980929, Example 74)
Affinity DataIC50: 4.28nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396362BDBM396362(US9980929, Example 64)
Affinity DataIC50: 4.47nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396361BDBM396361(US9980929, Example 63)
Affinity DataIC50: 4.53nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396348BDBM396348(US9980929, Example 46)
Affinity DataIC50: 6nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396367BDBM396367(US9980929, Example 69)
Affinity DataIC50: 6.07nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396330BDBM396330(US9980929, Example 28)
Affinity DataIC50: 9nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396326BDBM396326(US9980929, Example 24)
Affinity DataIC50: 10nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396338BDBM396338(US9980929, Example 36)
Affinity DataIC50: 10nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396349BDBM396349(US9980929, Example 48)
Affinity DataIC50: 10nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396350BDBM396350(US9980929, Example 50)
Affinity DataIC50: 10nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396369BDBM396369(US9980929, Example 71)
Affinity DataIC50: 10.1nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396364BDBM396364(US9980929, Example 66)
Affinity DataIC50: 10.6nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396325BDBM396325(US9980929, Example 23)
Affinity DataIC50: 15nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396321BDBM396321(US9980929, Example 19)
Affinity DataIC50: 15nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396354BDBM396354(US9980929, Example 56)
Affinity DataIC50: 15.1nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396331BDBM396331(US9980929, Example 29)
Affinity DataIC50: 20nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396332BDBM396332(US9980929, Example 30)
Affinity DataIC50: 20nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396351BDBM396351(US9980929, Example 52)
Affinity DataIC50: 23nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396335BDBM396335(US9980929, Example 33)
Affinity DataIC50: 25nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396340BDBM396340(US9980929, Example 38)
Affinity DataIC50: 30nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396337BDBM396337(US9980929, Example 35)
Affinity DataIC50: 35nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396314BDBM396314(US9980929, Example 12)
Affinity DataIC50: 35nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396306BDBM396306(US9980929, Example 4)
Affinity DataIC50: 37nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396371BDBM396371(US9980929, Example 73)
Affinity DataIC50: 37.3nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396323BDBM396323(US9980929, Example 21)
Affinity DataIC50: 45nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396374BDBM396374(US9980929, Example 76)
Affinity DataIC50: 48.3nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396368BDBM396368(US9980929, Example 70)
Affinity DataIC50: 48.6nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396334BDBM396334(US9980929, Example 32)
Affinity DataIC50: 50nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396366BDBM396366(US9980929, Example 68)
Affinity DataIC50: 50.5nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396313BDBM396313(US9980929, Example 11)
Affinity DataIC50: 55nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396365BDBM396365(US9980929, Example 67)
Affinity DataIC50: 56.6nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396316BDBM396316(US9980929, Example 14)
Affinity DataIC50: 58nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396370BDBM396370(US9980929, Example 72)
Affinity DataIC50: 58.9nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396357BDBM396357(US9980929, Example 59)
Affinity DataIC50: 59nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396342BDBM396342(US9980929, Example 40)
Affinity DataIC50: 60nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396308BDBM396308(US9980929, Example 6)
Affinity DataIC50: 60nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396324BDBM396324(US9980929, Example 22)
Affinity DataIC50: 60nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396356BDBM396356(US9980929, Example 58)
Affinity DataIC50: 60.2nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396333BDBM396333(US9980929, Example 31)
Affinity DataIC50: 65nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396319BDBM396319(US9980929, Example 17)
Affinity DataIC50: 70nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396336BDBM396336(US9980929, Example 34)
Affinity DataIC50: 70nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396347BDBM396347(US9980929, Example 45)
Affinity DataIC50: 70nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396355BDBM396355(US9980929, Example 57)
Affinity DataIC50: 77.8nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396341BDBM396341(US9980929, Example 39)
Affinity DataIC50: 80nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396311BDBM396311(US9980929, Example 9)
Affinity DataIC50: 80nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetSerine protease HTRA1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 396318BDBM396318(US9980929, Example 16)
Affinity DataIC50: 90nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

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