Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50008606
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075292BDBM50075292((R)-6-Amino-2-{(2R,3S)-3-(1H-indol-3-yl)-2-[3-(3-p...)
Affinity DataKi:  1nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075271BDBM50075271((R)-6-Amino-2-{(2R,3S)-3-(1H-indol-3-yl)-2-[2-oxo-...)
Affinity DataKi:  1.30nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075283BDBM50075283((R)-6-Amino-2-{(2R,3S)-3-(1H-indol-3-yl)-2-[2-oxo-...)
Affinity DataKi:  1.40nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075278BDBM50075278(methyl 6-amino-2-[2-(1H-3-indolyl)-1-spiro[2,3-dih...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity was evaluated against mouse Somatostatin receptor type 2 (mSSTR-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075273BDBM50075273((2R,3S)-N-(5-Amino-[1,3]dioxan-2-ylmethyl)-3-(1H-i...)
Affinity DataKi:  2.10nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075286BDBM50075286((R)-6-Amino-2-{(2R,3S)-3-(1H-indol-3-yl)-2-[3-meth...)
Affinity DataKi:  2.20nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075275BDBM50075275((R)-6-Amino-2-{(2R,3S)-3-(1H-indol-3-yl)-2-[2-oxo-...)
Affinity DataKi:  3.60nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075290BDBM50075290((2R,3S)-N-(5-Amino-[1,3]dioxan-2-ylmethyl)-2-[3-(3...)
Affinity DataKi:  4.60nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075276BDBM50075276((R)-6-Amino-2-{(2R,3S)-3-(1H-indol-3-yl)-2-[2-oxo-...)
Affinity DataKi:  5.90nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075280BDBM50075280((R)-6-Amino-2-{(2R,3S)-3-(1H-indol-3-yl)-2-[2-oxo-...)
Affinity DataKi:  6.30nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075279BDBM50075279((2R,3S)-N-(5-Amino-[1,3]dioxan-2-ylmethyl)-2-[3-(3...)
Affinity DataKi:  7.30nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075272BDBM50075272((2R,3S)-N-(5-Amino-[1,3]dioxan-2-ylmethyl)-2-[3-(3...)
Affinity DataKi:  8.5nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 (hSSTR-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075272BDBM50075272((2R,3S)-N-(5-Amino-[1,3]dioxan-2-ylmethyl)-2-[3-(3...)
Affinity DataKi:  8.5nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075274BDBM50075274(1'N-[1-(5-aminopentylcarbamoyl)-2-(1H-3-indolyl)-(...)
Affinity DataKi: >10nMAssay Description:In vitro binding affinity was evaluated against mouse Somatostatin receptor type 2 (mSSTR-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075281BDBM50075281(1'N-[1-(5-aminopentylcarbamoyl)-2-(1H-3-indolyl)-(...)
Affinity DataKi:  10nMAssay Description:In vitro binding affinity was evaluated against mouse Somatostatin receptor type 2 (mSSTR-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075289BDBM50075289(1-[5-amino-1-methyloxycarbonyl-(1R)-pentylcarbamoy...)
Affinity DataKi:  10nMAssay Description:In vitro binding affinity was evaluated against mouse Somatostatin receptor type 2 (mSSTR-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075277BDBM50075277((2R,3S)-N-(5-Amino-[1,3]dioxan-2-ylmethyl)-3-(1H-i...)
Affinity DataKi:  11nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075293BDBM50075293((R)-6-Amino-2-{(2R,3S)-3-(1H-indol-3-yl)-2-[3-(1-m...)
Affinity DataKi:  12nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075273BDBM50075273((2R,3S)-N-(5-Amino-[1,3]dioxan-2-ylmethyl)-3-(1H-i...)
Affinity DataKi:  14nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075287BDBM50075287((R)-6-Amino-2-[(2R,3S)-2-(3-benzyl-2-oxo-imidazoli...)
Affinity DataKi:  14nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075284BDBM50075284((2R,3S)-N-(5-Amino-[1,3]dioxan-2-ylmethyl)-3-(1H-i...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075280BDBM50075280((R)-6-Amino-2-{(2R,3S)-3-(1H-indol-3-yl)-2-[2-oxo-...)
Affinity DataKi:  40nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075285BDBM50075285((2R,3S)-N-(5-Amino-[1,3]dioxan-2-ylmethyl)-3-(1H-i...)
Affinity DataKi:  40nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075288BDBM50075288((R)-6-Amino-2-[(2R,3S)-3-(1H-indol-3-yl)-2-(2-oxo-...)
Affinity DataKi:  47nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075282BDBM50075282((R)-6-Amino-2-[(2R,3S)-2-(3-biphenyl-3-yl-2-oxo-im...)
Affinity DataKi:  80nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075275BDBM50075275((R)-6-Amino-2-{(2R,3S)-3-(1H-indol-3-yl)-2-[2-oxo-...)
Affinity DataKi:  83nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 4 (hSSTR-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075291BDBM50075291((2R,3S)-N-(5-Amino-[1,3]dioxan-2-ylmethyl)-3-(1H-i...)
Affinity DataKi:  122nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 2 in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075275BDBM50075275((R)-6-Amino-2-{(2R,3S)-3-(1H-indol-3-yl)-2-[2-oxo-...)
Affinity DataKi:  284nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 5 (hSSTR-5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075275BDBM50075275((R)-6-Amino-2-{(2R,3S)-3-(1H-indol-3-yl)-2-[2-oxo-...)
Affinity DataKi:  712nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 1 (hSSTR-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075275BDBM50075275((R)-6-Amino-2-{(2R,3S)-3-(1H-indol-3-yl)-2-[2-oxo-...)
Affinity DataKi:  1.29E+3nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 3 (hSSTR-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075273BDBM50075273((2R,3S)-N-(5-Amino-[1,3]dioxan-2-ylmethyl)-3-(1H-i...)
Affinity DataKi:  1.40E+3nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 5 (hSSTR-5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075273BDBM50075273((2R,3S)-N-(5-Amino-[1,3]dioxan-2-ylmethyl)-3-(1H-i...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity was evaluated against human Somatostatin receptor type 3 (hSSTR-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed