Compile Data Set for Download or QSAR
Report error Found 100 Enz. Inhib. hit(s) with all data for entry = 50008765
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076926BDBM50076926(1,11-dihydroxy-5,7-dioxo-6-phenylcarboxamido-12-(3...)
Affinity DataEC50:  52nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076938BDBM50076938(2-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50:  70nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076925BDBM50076925(1,11-dihydroxy-5,7-dioxo-6-(2-pyridylcarboxamido)-...)
Affinity DataEC50:  90nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076944BDBM50076944(4-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50:  160nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076934BDBM50076934(1N-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-...)
Affinity DataEC50:  170nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076937BDBM50076937(6-phenylamino-1,11-dihydroxy-12-(3,4,5-trihydroxy-...)
Affinity DataEC50:  250nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076941BDBM50076941(1,11-dihydroxy-6-(4-methylphenylsulfonamido)-5,7-d...)
Affinity DataEC50:  270nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076923BDBM50076923(6-amino-1,11-dihydroxy-12-(3,4,5-trihydroxy-6-hydr...)
Affinity DataEC50:  270nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076933BDBM50076933(1,11-dihydroxy-6-(3-hydroxybenzylamino)-12-(3,4,5-...)
Affinity DataEC50:  300nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076940BDBM50076940(1,11-dihydroxy-6-methylamino-12-(3,4,5-trihydroxy-...)
Affinity DataEC50:  350nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076921BDBM50076921(6-amino-1,11-dihydroxy-12-(3,4,5-trihydroxy-6-hydr...)
Affinity DataEC50:  360nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076920BDBM50076920(1,11-dihydroxy-6-(2-hydroxyethylamino)-12-(3,4,5-t...)
Affinity DataEC50:  430nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076931BDBM50076931(1N-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-...)
Affinity DataEC50:  480nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076929BDBM50076929(1,11-dihydroxy-5,7-dioxo-6-(2-pyridylcarboxamido)-...)
Affinity DataEC50:  550nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076922BDBM50076922(1,11-dihydroxy-6-(2-hydroxy-1-hydroxymethylethylam...)
Affinity DataEC50:  580nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076924BDBM50076924(N-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50:  580nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076943BDBM50076943(N-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50:  700nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076935BDBM50076935(6-(2,3-dihydroxypropylamino)-1,11-dihydroxy-12-(3,...)
Affinity DataEC50:  1.00E+3nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076930BDBM50076930(1N-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-...)
Affinity DataEC50:  1.00E+3nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076936BDBM50076936(1,11-dihydroxy-6-propylamino-12-(3,4,5-trihydroxy-...)
Affinity DataEC50:  1.20E+3nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076927BDBM50076927(1N-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-...)
Affinity DataEC50:  2.80E+3nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076928BDBM50076928(1,11-dihydroxy-6,7,12,13-tetrahydro-5H-indolo[2,3-...)
Affinity DataEC50: >3.00E+3nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073855BDBM50073855(1,11-dihydroxy-12-(3,4,5-trihydroxy-6-hydroxymethy...)
Affinity DataEC50:  3.00E+3nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076942BDBM50076942(6-ethylamino-1,11-dihydroxy-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50:  3.50E+3nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073855BDBM50073855(1,11-dihydroxy-12-(3,4,5-trihydroxy-6-hydroxymethy...)
Affinity DataIC50: 3.80E+3nMAssay Description:In vitro activity evaluated against protein kinase C (using histone II-As as a substrate)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076937BDBM50076937(6-phenylamino-1,11-dihydroxy-12-(3,4,5-trihydroxy-...)
Affinity DataIC50: 6.80E+3nMAssay Description:In vitro activity evaluated against protein kinase C (using histone II-As as a substrate)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076932BDBM50076932(2-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50:  9.50E+3nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076939BDBM50076939(6-dimethylamino-1,11-dihydroxy-12-(3,4,5-trihydrox...)
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076941BDBM50076941(1,11-dihydroxy-6-(4-methylphenylsulfonamido)-5,7-d...)
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro activity evaluated against protein kinase C (using histone II-As as a substrate)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076933BDBM50076933(1,11-dihydroxy-6-(3-hydroxybenzylamino)-12-(3,4,5-...)
Affinity DataIC50: 1.30E+4nMAssay Description:In vitro activity evaluated against protein kinase C (using histone II-As as a substrate)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076944BDBM50076944(4-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataIC50: 2.30E+4nMAssay Description:In vitro activity evaluated against protein kinase C (using histone II-As as a substrate)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076928BDBM50076928(1,11-dihydroxy-6,7,12,13-tetrahydro-5H-indolo[2,3-...)
Affinity DataIC50: 2.90E+4nMAssay Description:In vitro activity against Epidermal growth factor receptor (using poly(Glu4Tyr1) as a substrate)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076926BDBM50076926(1,11-dihydroxy-5,7-dioxo-6-phenylcarboxamido-12-(3...)
Affinity DataIC50: 3.50E+4nMAssay Description:In vitro activity evaluated against protein kinase C (using histone II-As as a substrate)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076931BDBM50076931(1N-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-...)
Affinity DataIC50: 3.60E+4nMAssay Description:In vitro activity evaluated against protein kinase C (using histone II-As as a substrate)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076928BDBM50076928(1,11-dihydroxy-6,7,12,13-tetrahydro-5H-indolo[2,3-...)
Affinity DataIC50: 4.00E+4nMAssay Description:In vitro activity evaluated against protein kinase C (using histone II-As as a substrate)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076925BDBM50076925(1,11-dihydroxy-5,7-dioxo-6-(2-pyridylcarboxamido)-...)
Affinity DataIC50: 4.10E+4nMAssay Description:In vitro activity evaluated against protein kinase C (using histone II-As as a substrate)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076941BDBM50076941(1,11-dihydroxy-6-(4-methylphenylsulfonamido)-5,7-d...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro activity against topoisomerase-2 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076923BDBM50076923(6-amino-1,11-dihydroxy-12-(3,4,5-trihydroxy-6-hydr...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro activity against topoisomerase-2 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076936BDBM50076936(1,11-dihydroxy-6-propylamino-12-(3,4,5-trihydroxy-...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro activity against topoisomerase-2 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076943BDBM50076943(N-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro activity against topoisomerase-2 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076942BDBM50076942(6-ethylamino-1,11-dihydroxy-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro activity against topoisomerase-2 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076940BDBM50076940(1,11-dihydroxy-6-methylamino-12-(3,4,5-trihydroxy-...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro activity against topoisomerase-2 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076928BDBM50076928(1,11-dihydroxy-6,7,12,13-tetrahydro-5H-indolo[2,3-...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro activity against topoisomerase-2 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076927BDBM50076927(1N-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro activity against topoisomerase-2 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076925BDBM50076925(1,11-dihydroxy-5,7-dioxo-6-(2-pyridylcarboxamido)-...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro activity against topoisomerase-2 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076929BDBM50076929(1,11-dihydroxy-5,7-dioxo-6-(2-pyridylcarboxamido)-...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro activity against topoisomerase-2 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076931BDBM50076931(1N-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro activity against topoisomerase-2 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076938BDBM50076938(2-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro activity against topoisomerase-2 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073855BDBM50073855(1,11-dihydroxy-12-(3,4,5-trihydroxy-6-hydroxymethy...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro activity against topoisomerase-2 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076932BDBM50076932(2-[1,11-dihydroxy-5,7-dioxo-12-(3,4,5-trihydroxy-6...)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro activity against topoisomerase-2 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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