Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50009044
LigandChemical structure of BindingDB Monomer ID 50079667BDBM50079667((S)-2-[3-({(4-Cyano-benzyl)-[3-(4-cyano-benzyl)-3H...)
Affinity DataIC50: 0.410nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079661BDBM50079661((S)-2-[3-({(4-Cyano-benzyl)-[3-(4-cyano-benzyl)-3H...)
Affinity DataIC50: 5nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079664BDBM50079664((S)-2-(3-{[(4-Cyano-benzyl)-(3H-imidazol-4-ylmethy...)
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant Ha-Ras by bovine brain farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079674BDBM50079674((S)-2-[3-({Butyl-[3-(4-cyano-benzyl)-3H-imidazol-4...)
Affinity DataIC50: 14nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079666BDBM50079666((S)-2-[3-({[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmet...)
Affinity DataIC50: 23nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079675BDBM50079675((S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-(4-nitro-benzy...)
Affinity DataIC50: 27nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079663BDBM50079663((S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-naphthalen-2-y...)
Affinity DataIC50: 55nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079660BDBM50079660((S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-naphthalen-1-y...)
Affinity DataIC50: 58nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079678BDBM50079678((S)-2-[3-({Butyl-[3-(4-cyano-benzyl)-3H-imidazol-4...)
Affinity DataIC50: 183nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079676BDBM50079676((S)-2-(3-{[Benzyl-(1H-imidazol-4-ylmethyl)-amino]-...)
Affinity DataIC50: 255nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079677BDBM50079677((S)-2-[3-({[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmet...)
Affinity DataIC50: 260nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079673BDBM50079673((S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-phenethyl-amin...)
Affinity DataIC50: 300nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079672BDBM50079672((S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-(4-methoxy-ben...)
Affinity DataIC50: 355nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079671BDBM50079671((S)-2-(3-{[Bis-(1H-imidazol-4-ylmethyl)-amino]-met...)
Affinity DataIC50: 870nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant Ha-Ras by bovine brain farnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079670BDBM50079670((S)-2-(3-{[(4-Cyano-benzyl)-(3H-imidazol-4-ylmethy...)
Affinity DataIC50: 1.08E+3nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079668BDBM50079668((S)-2-(3-{[Bis-(4-nitro-benzyl)-amino]-methyl}-ben...)
Affinity DataIC50: 1.60E+3nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079659BDBM50079659((S)-2-(3-{[Benzoyl-(1H-imidazol-4-ylmethyl)-amino]...)
Affinity DataIC50: 1.75E+3nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079664BDBM50079664((S)-2-(3-{[(4-Cyano-benzyl)-(3H-imidazol-4-ylmethy...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of geranylgeranyl transferase I (GGTase-I)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079669BDBM50079669((S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-methyl-amino]-...)
Affinity DataIC50: 1.20E+4nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079671BDBM50079671((S)-2-(3-{[Bis-(1H-imidazol-4-ylmethyl)-amino]-met...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of geranylgeranyl transferase I (GGTase-I)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079665BDBM50079665((S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl}...)
Affinity DataIC50: 5.76E+4nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079662BDBM50079662((S)-4-Methylsulfanyl-2-{3-[(4-nitro-benzylamino)-m...)
Affinity DataIC50: 8.00E+4nMAssay Description:Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed