Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50036744
LigandChemical structure of BindingDB Monomer ID 50079974BDBM50079974((S)-2-[2-({(S)-3-Methyl-2-[2-(3-naphthalen-1-ylmet...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079961BDBM50079961((S)-2-[2-({(S)-3-Methyl-2-[2-(3-naphthalen-2-ylmet...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50369443BDBM50369443(CHEMBL252953)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079956BDBM50079956((S)-2-[2-({(S)-2-[2-(3-Benzyl-3H-imidazol-4-yl)-ac...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079966BDBM50079966((S)-2-{2-[((S)-3-Methyl-2-{2-[3-(4-nitro-benzyl)-3...)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079978BDBM50079978((S)-2-{2-[((S)-2-{2-[3-((E)-3,7-Dimethyl-octa-2,6-...)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079971BDBM50079971((S)-2-{2-[((S)-2-{2-[3-(4-Fluoro-benzyl)-3H-imidaz...)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079968BDBM50079968((S)-2-{2-[((S)-2-{2-[3-(4-Methoxy-benzyl)-3H-imida...)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079963BDBM50079963((S)-4-Methylsulfanyl-2-{2-[((S)-3-methyl-2-{2-[3-(...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079962BDBM50079962((S)-2-[2-({(S)-3-Methyl-2-[2-(3-pyridin-4-ylmethyl...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079964BDBM50079964((S)-2-[2-({(S)-3-Methyl-2-[2-(3-quinolin-2-ylmethy...)
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079965BDBM50079965((S)-2-{2-[((S)-3-Methyl-2-{2-[1-(4-nitro-benzyl)-1...)
Affinity DataIC50: 10nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079975BDBM50079975((S)-2-{2-[((S)-2-{2-[3-(4-Cyano-benzyl)-3H-imidazo...)
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50369443BDBM50369443(CHEMBL252953)
Affinity DataIC50: 67nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079976BDBM50079976((S)-2-[2-({(S)-3-Methyl-2-[2-(1-pyridin-4-ylmethyl...)
Affinity DataIC50: 74nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079979BDBM50079979((S)-2-[2-({(S)-2-[2-(1-Benzyl-1H-imidazol-4-yl)-ac...)
Affinity DataIC50: 82nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079966BDBM50079966((S)-2-{2-[((S)-3-Methyl-2-{2-[3-(4-nitro-benzyl)-3...)
Affinity DataIC50: 92nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079968BDBM50079968((S)-2-{2-[((S)-2-{2-[3-(4-Methoxy-benzyl)-3H-imida...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079971BDBM50079971((S)-2-{2-[((S)-2-{2-[3-(4-Fluoro-benzyl)-3H-imidaz...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079956BDBM50079956((S)-2-[2-({(S)-2-[2-(3-Benzyl-3H-imidazol-4-yl)-ac...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079978BDBM50079978((S)-2-{2-[((S)-2-{2-[3-((E)-3,7-Dimethyl-octa-2,6-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079961BDBM50079961((S)-2-[2-({(S)-3-Methyl-2-[2-(3-naphthalen-2-ylmet...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079963BDBM50079963((S)-4-Methylsulfanyl-2-{2-[((S)-3-methyl-2-{2-[3-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079974BDBM50079974((S)-2-[2-({(S)-3-Methyl-2-[2-(3-naphthalen-1-ylmet...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079964BDBM50079964((S)-2-[2-({(S)-3-Methyl-2-[2-(3-quinolin-2-ylmethy...)
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of [3H]GGPP incorporation into recombinant human Ha-RasCVLL by Geranylgeranyl transferase from bovine brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed