Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50009174
TargetSerine protease 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080895BDBM50080895(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataKi:  14nMAssay Description:Compound was tested for the binding affinity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080908BDBM50080908(2-[(S)-2-Benzyl-3,6-dioxo-4-(3-phenyl-propyl)-pipe...)
Affinity DataKi:  24nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080895BDBM50080895(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataKi:  30nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080903BDBM50080903(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataKi:  40nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080905BDBM50080905(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataKi:  43nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080895BDBM50080895(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080896BDBM50080896(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataKi:  65nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080907BDBM50080907(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataKi:  75nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080897BDBM50080897(2-[(S)-2-Benzyl-3,6-dioxo-4-(3-phenyl-propyl)-pipe...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080904BDBM50080904(2-[(S)-2-Butyl-3,6-dioxo-4-(3-phenyl-propyl)-piper...)
Affinity DataKi:  98nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080900BDBM50080900(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataKi:  105nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080897BDBM50080897(2-[(S)-2-Benzyl-3,6-dioxo-4-(3-phenyl-propyl)-pipe...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080901BDBM50080901(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataKi:  140nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080906BDBM50080906(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataKi:  165nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080903BDBM50080903(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080898BDBM50080898(2-[(S)-2-sec-Butyl-3,6-dioxo-4-(3-phenyl-propyl)-p...)
Affinity DataKi:  200nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080908BDBM50080908(2-[(S)-2-Benzyl-3,6-dioxo-4-(3-phenyl-propyl)-pipe...)
Affinity DataIC50: 240nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080905BDBM50080905(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 350nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080907BDBM50080907(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 430nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080899BDBM50080899(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataKi:  495nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080900BDBM50080900(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 590nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080902BDBM50080902(2-[2-Benzhydryl-3,6-dioxo-4-(3-phenyl-propyl)-pipe...)
Affinity DataIC50: 750nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080896BDBM50080896(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 760nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080910BDBM50080910(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080901BDBM50080901(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080904BDBM50080904(2-[(S)-2-Butyl-3,6-dioxo-4-(3-phenyl-propyl)-piper...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080909BDBM50080909(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080898BDBM50080898(2-[(S)-2-sec-Butyl-3,6-dioxo-4-(3-phenyl-propyl)-p...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080905BDBM50080905(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080906BDBM50080906(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080899BDBM50080899(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080902BDBM50080902(2-[2-Benzhydryl-3,6-dioxo-4-(3-phenyl-propyl)-pipe...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080911BDBM50080911(2-((S)-4-Benzyl-2-naphthalen-2-ylmethyl-3,6-dioxo-...)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080907BDBM50080907(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080896BDBM50080896(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080901BDBM50080901(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080895BDBM50080895(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080900BDBM50080900(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080903BDBM50080903(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 3.34E+4nMAssay Description:Inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080904BDBM50080904(2-[(S)-2-Butyl-3,6-dioxo-4-(3-phenyl-propyl)-piper...)
Affinity DataIC50: 4.27E+4nMAssay Description:Inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080909BDBM50080909(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 7.48E+4nMAssay Description:Inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50080899BDBM50080899(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 9.12E+4nMAssay Description:Inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed