Compile Data Set for Download or QSAR
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Found 15 Enz. Inhib. hit(s) with all data for entry = 50009453
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Louisville

Curated by ChEMBL
LigandPNGBDBM50083731((6R,9R)-10-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propi...)
Affinity DataKi:  0.290nMAssay Description:Compound was tested for binding affinity against mu opioid receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Louisville

Curated by ChEMBL
LigandPNGBDBM50083732((6R,9R)-10-((S)-2-Amino-3-phenyl-propionylamino)-7...)
Affinity DataKi:  14nMAssay Description:Compound was tested for binding affinity against mu opioid receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Louisville

Curated by ChEMBL
LigandPNGBDBM50083734(2-Amino-N-[(R)-6-(4-hydroxy-benzyl)-3-methyl-2,5,8...)
Affinity DataIC50:  0.110nMAssay Description:In vitro mu opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in guinea pi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Louisville

Curated by ChEMBL
LigandPNGBDBM50083734(2-Amino-N-[(R)-6-(4-hydroxy-benzyl)-3-methyl-2,5,8...)
Affinity DataIC50:  0.540nMAssay Description:In vitro delta opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in mouse ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Louisville

Curated by ChEMBL
LigandPNGBDBM50083732((6R,9R)-10-((S)-2-Amino-3-phenyl-propionylamino)-7...)
Affinity DataIC50:  9.10nMAssay Description:Compound was tested for its ability to activate mu opioid receptor in GPI bioassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Louisville

Curated by ChEMBL
LigandPNGBDBM50083736(13-((S)-2-Amino-3-phenyl-propionylamino)-7-(4-nitr...)
Affinity DataIC50:  13nMAssay Description:Compound was tested for moderate potency against mu opioid receptor in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Louisville

Curated by ChEMBL
LigandPNGBDBM50083730((R)-2-Amino-N-[(S)-6-(4-hydroxy-benzyl)-3-(1H-indo...)
Affinity DataIC50:  17.7nMAssay Description:In vitro delta opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in mouse ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Louisville

Curated by ChEMBL
LigandPNGBDBM50083730((R)-2-Amino-N-[(S)-6-(4-hydroxy-benzyl)-3-(1H-indo...)
Affinity DataIC50:  18nMAssay Description:In vitro mu opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in guinea pi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Louisville

Curated by ChEMBL
LigandPNGBDBM50083729(2-Amino-N-((R)-6-benzyl-3-methyl-2,5,8-trioxo-1,4,...)
Affinity DataIC50:  30nMAssay Description:In vitro mu opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in guinea pi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Louisville

Curated by ChEMBL
LigandPNGBDBM50083729(2-Amino-N-((R)-6-benzyl-3-methyl-2,5,8-trioxo-1,4,...)
Affinity DataIC50:  30.4nMAssay Description:In vitro delta opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in mouse ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Louisville

Curated by ChEMBL
LigandPNGBDBM50083737(13-((S)-2-Amino-3-phenyl-propionylamino)-7-benzyl-...)
Affinity DataIC50:  42nMAssay Description:Compound was tested for moderate potency against mu opioid receptor in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Louisville

Curated by ChEMBL
LigandPNGBDBM50083733(2-Amino-N-[(S)-6-(4-hydroxy-benzyl)-3-(1H-indol-2-...)
Affinity DataIC50:  627nMAssay Description:In vitro mu opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in guinea pi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Louisville

Curated by ChEMBL
LigandPNGBDBM50083735((R)-2-Amino-N-[(R)-6-(4-hydroxy-benzyl)-3-methyl-2...)
Affinity DataIC50:  1.83E+3nMAssay Description:In vitro mu opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in guinea pi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Louisville

Curated by ChEMBL
LigandPNGBDBM50083733(2-Amino-N-[(S)-6-(4-hydroxy-benzyl)-3-(1H-indol-2-...)
Affinity DataIC50:  8.13E+3nMAssay Description:In vitro delta opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in mouse ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Louisville

Curated by ChEMBL
LigandPNGBDBM50083735((R)-2-Amino-N-[(R)-6-(4-hydroxy-benzyl)-3-methyl-2...)
Affinity DataIC50:  9.33E+3nMAssay Description:In vitro delta opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in mouse ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed