Compile Data Set for Download or QSAR
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Found 8 Enz. Inhib. hit(s) with all data for entry = 50009905
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089021((8R,13R)-13-{[1-Acetyl-3-(4-hydroxy-phenyl)-pyrrol...)
Affinity DataIC50:  0.100nMAssay Description:Compound was evaluated for VCAM-VLA-4 antagonistic activity using solid phase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089023((8S,13R)-13-{[1-Acetyl-3-(4-hydroxy-phenyl)-pyrrol...)
Affinity DataIC50:  0.5nMAssay Description:Compound was evaluated for VCAM-VLA-4 antagonistic activity using Ramos cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089019((8R,13R)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-prop...)
Affinity DataIC50:  0.5nMAssay Description:Compound was evaluated for VCAM-VLA-4 antagonistic activity using solid phase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089021((8R,13R)-13-{[1-Acetyl-3-(4-hydroxy-phenyl)-pyrrol...)
Affinity DataIC50:  1.5nMAssay Description:Compound was evaluated for VCAM-VLA-4 antagonistic activity using solid phase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089024((8R,13S)-13-{[1-Acetyl-3-(4-hydroxy-phenyl)-pyrrol...)
Affinity DataIC50:  2.70nMAssay Description:Compound was evaluated for VCAM-VLA-4 antagonistic activity using solid phase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089023((8S,13R)-13-{[1-Acetyl-3-(4-hydroxy-phenyl)-pyrrol...)
Affinity DataIC50:  20nMAssay Description:Compound was evaluated for VCAM-VLA-4 antagonistic activity using Ramos cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089022((8S,14S)-14-{[1-Acetyl-3-(4-hydroxy-phenyl)-pyrrol...)
Affinity DataIC50:  35nMAssay Description:Compound was evaluated for VCAM-VLA-4 antagonistic activity using solid phase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089024((8R,13S)-13-{[1-Acetyl-3-(4-hydroxy-phenyl)-pyrrol...)
Affinity DataIC50:  220nMAssay Description:Compound was evaluated for VCAM-VLA-4 antagonistic activity using Ramos cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed