Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50010064
Target5-hydroxytryptamine receptor 6(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090529(2-[1-(Naphthalene-1-sulfonyl)-1H-indol-6-yl]-octah...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090527(1-(Naphthalene-1-sulfonyl)-6-(octahydro-indolizin-...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090527(1-(Naphthalene-1-sulfonyl)-6-(octahydro-indolizin-...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM28583(CHEMBL431298 | SB 271046 | 5-chloro-N-[4-methoxy-3...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090530(6-(1,2,3,5,8,8a-Hexahydro-indolizin-7-yl)-1-(napht...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090533(2-[1-(Naphthalene-1-sulfonyl)-1H-indol-6-yl]-octah...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090532(2-[1-(Naphthalene-2-sulfonyl)-1H-indol-6-yl]-octah...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090536(2-[1-(Toluene-4-sulfonyl)-1H-indol-6-yl]-octahydro...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090535(2-[1-(2,4-Difluoro-benzenesulfonyl)-1H-indol-6-yl]...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090531(7-[1-(Naphthalene-1-sulfonyl)-1H-indol-6-yl]-octah...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090534(2-[1-(Toluene-4-sulfonyl)-1H-indol-6-yl]-octahydro...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090526(2-(1-Benzenesulfonyl-1H-indol-6-yl)-octahydro-pyri...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenylate cyclase type 5(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090529(2-[1-(Naphthalene-1-sulfonyl)-1H-indol-6-yl]-octah...)
Affinity DataIC50: 7.20nMAssay Description:Antagonistic activity evaluated in adenylyl cyclase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090524(Ro-63-0563 | 4-Amino-N-(2,6-bis-methylamino-pyridi...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090528(Ro-04-6790 | 4-Amino-N-(2,6-bis-dimethylamino-pyri...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]LSD from human 5-hydroxytryptamine 6 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed