Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50010136
TargetC-C chemokine receptor type 5(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50088301BDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50: 1.40nMAssay Description:Compound was evaluated for the antagonist activity against C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50088301BDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50: 27nMAssay Description:Compound was evaluated for the antagonist activity against C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091440BDBM50091440(1'-{2-[2-(4-fluorophenyl)-5-methyl-1,3-oxazol-4-yl...)
Affinity DataIC50: 32nMAssay Description:Compound was evaluated for the antagonist activity against C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091438BDBM50091438((E)-3-(3,4-dichlorophenyl)-N-(5-(4-(5-hydroxy-1H-i...)
Affinity DataKi:  50nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091449BDBM50091449(TCMDC-139325 | (E)-3-(3,4-Dichloro-phenyl)-N-{5-[4...)
Affinity DataKi:  79nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091457BDBM50091457((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-2-m...)
Affinity DataKi:  234nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091454BDBM50091454((E)-3-(4-Bromo-phenyl)-N-{5-[4-(1H-indol-3-yl)-pip...)
Affinity DataKi:  350nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091451BDBM50091451((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(6-hydroxy-1H-...)
Affinity DataKi:  360nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091461BDBM50091461((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(4-hydroxy-1H-...)
Affinity DataKi:  360nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091458BDBM50091458((E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-...)
Affinity DataKi:  420nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091465BDBM50091465((E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-...)
Affinity DataKi:  460nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091445BDBM50091445((E)-3-(4-Chloro-phenyl)-N-{5-[4-(1H-indol-3-yl)-pi...)
Affinity DataKi:  520nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091471BDBM50091471(TCMDC-139236 | (E)-N-{5-[4-(1H-Indol-3-yl)-piperid...)
Affinity DataKi:  550nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091460BDBM50091460((E)-3-(3-Chloro-phenyl)-N-{5-[4-(1H-indol-3-yl)-pi...)
Affinity DataKi:  560nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091470BDBM50091470((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-methoxy-1H-...)
Affinity DataKi:  590nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091442BDBM50091442(TCMDC-139333 | (E)-3-(3,4-Dichloro-phenyl)-N-{4-[4...)
Affinity DataKi:  660nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091467BDBM50091467((E)-N-{5-[4-(1H-Indol-3-yl)-piperidin-1-yl]-pentyl...)
Affinity DataKi:  790nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091448BDBM50091448((E)-N-{5-[4-(1H-Indol-3-yl)-piperidin-1-yl]-pentyl...)
Affinity DataKi:  790nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091439BDBM50091439((E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)c...)
Affinity DataKi:  870nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091468BDBM50091468((E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-...)
Affinity DataKi:  1.20E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091443BDBM50091443((E)-3-Biphenyl-4-yl-N-{5-[4-(1H-indol-3-yl)-piperi...)
Affinity DataKi:  1.45E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091441BDBM50091441(1-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-3-(3...)
Affinity DataKi:  1.60E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091447BDBM50091447((E)-3-(4-tert-Butyl-phenyl)-N-{5-[4-(1H-indol-3-yl...)
Affinity DataKi:  1.70E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091453BDBM50091453((E)-N-(3-(4-(1H-indol-3-yl)piperidin-1-yl)propyl)-...)
Affinity DataKi:  2.50E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091446BDBM50091446((E)-3-(4-Cyano-phenyl)-N-{5-[4-(1H-indol-3-yl)-pip...)
Affinity DataKi:  2.80E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091452BDBM50091452((E)-3-(4-Acetylamino-phenyl)-N-{5-[4-(1H-indol-3-y...)
Affinity DataKi:  2.90E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091456BDBM50091456(TCMDC-139364 | (E)-3-(3,4-Dichloro-phenyl)-N-{5-[4...)
Affinity DataKi:  4.20E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091438BDBM50091438((E)-3-(3,4-dichlorophenyl)-N-(5-(4-(5-hydroxy-1H-i...)
Affinity DataKi:  4.26E+3nMAssay Description:Compound was evaluated for the antagonist activity against C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091466BDBM50091466((E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-...)
Affinity DataKi:  4.40E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091464BDBM50091464(2-(3,4-Dichloro-phenyl)-N-{5-[4-(1H-indol-3-yl)-pi...)
Affinity DataKi:  4.40E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091459BDBM50091459(TCMDC-139112 | N-(5-(4-(1H-indol-3-yl)piperidin-1-...)
Affinity DataKi:  5.10E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091444BDBM50091444(Biphenyl-4-carboxylic acid {5-[4-(1H-indol-3-yl)-p...)
Affinity DataKi:  5.30E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091444BDBM50091444(Biphenyl-4-carboxylic acid {5-[4-(1H-indol-3-yl)-p...)
Affinity DataKi:  5.40E+3nMAssay Description:Antagonist activity against C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091450BDBM50091450(3-(3,4-Dichloro-phenyl)-N-{5-[4-(1H-indol-3-yl)-pi...)
Affinity DataKi:  5.90E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091455BDBM50091455((E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-...)
Affinity DataKi:  6.30E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091472BDBM50091472(N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-4-br...)
Affinity DataKi:  7.10E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091462BDBM50091462((E)-3-(3,4-Dichloro-phenyl)-N-{2-[4-(1H-indol-3-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091469BDBM50091469(Biphenyl-4-carboxylic acid {6-[4-(1H-indol-3-yl)-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091463BDBM50091463(3,4-Dichloro-N-{5-[4-(1H-indol-3-yl)-piperidin-1-y...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed