Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 1334
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Institut Curie

LigandPNGBDBM10908(3-(dimethylamino)-4-[(3,5-dimethylphenyl)methyl]-5...)
Affinity DataIC50: 20nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2006
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Institut Curie

LigandPNGBDBM10903(4-[(3,5-dimethylphenyl)sulfanyl]-5-ethyl-6-methyl-...)
Affinity DataIC50: 30nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2006
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Institut Curie

LigandPNGBDBM10905(3-amino-4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-m...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2006
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Institut Curie

LigandPNGBDBM10906(3-amino-4-[(3,5-dimethylphenyl)carbonyl]-5-ethyl-6...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2006
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Institut Curie

LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 200nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2006
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Institut Curie

LigandPNGBDBM10907(4-(3,5-Dimethylbenzyl)-5-ethyl-3-formamido-6-methy...)
Affinity DataIC50: 200nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2006
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Institut Curie

LigandPNGBDBM10904(1-[(benzyloxy)methyl]-6-(phenylthio)-thymine | CHE...)
Affinity DataIC50: 300nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2006
Entry Details Article
PubMed