Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50010306
TargetSubstance-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50071484BDBM50071484(N-[(R)-4-(4-Acetylamino-4-phenyl-piperidin-1-yl)-2...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity towards Tachykinin receptor 2 in CHO cells using [3H]-neurokinin A as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093096BDBM50093096(2-[(1R,2S)-1-(3,5-Bis-trifluoromethyl-benzyloxymet...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity towards Tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093095BDBM50093095(2-[(S)-1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity towards Tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093088BDBM50093088(2-[1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-(...)
Affinity DataKi:  4nMAssay Description:Binding affinity towards Tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093092BDBM50093092(2-[(1S,2S)-1-(3,5-Bis-trifluoromethyl-benzyloxymet...)
Affinity DataKi:  5nMAssay Description:Binding affinity towards Tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093087BDBM50093087((R)-1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-d...)
Affinity DataKi:  7nMAssay Description:Binding affinity towards Tachykinin receptor 2 in CHO cells using [3H]-neurokinin A as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093091BDBM50093091(2-[(1R,2R)-1-(3,5-Bis-trifluoromethyl-benzyloxymet...)
Affinity DataKi:  9nMAssay Description:Binding affinity towards Tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093087BDBM50093087((R)-1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-d...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards Tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093086BDBM50093086(1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichl...)
Affinity DataKi:  21nMAssay Description:Binding affinity towards Tachykinin receptor 2 in CHO cells using [3H]-neurokinin A as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093093BDBM50093093(CHEMBL76334 | 1-(3,5-Bis-trifluoromethyl-benzyloxy...)
Affinity DataKi:  24nMAssay Description:Binding affinity towards Tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093090BDBM50093090(1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichl...)
Affinity DataKi:  25nMAssay Description:Binding affinity towards Tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093086BDBM50093086(1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichl...)
Affinity DataKi:  25nMAssay Description:Binding affinity towards Tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093089BDBM50093089((S)-1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-d...)
Affinity DataKi:  33nMAssay Description:Binding affinity towards Tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093093BDBM50093093(CHEMBL76334 | 1-(3,5-Bis-trifluoromethyl-benzyloxy...)
Affinity DataKi:  34nMAssay Description:Binding affinity towards Tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093091BDBM50093091(2-[(1R,2R)-1-(3,5-Bis-trifluoromethyl-benzyloxymet...)
Affinity DataKi:  34nMAssay Description:Binding affinity towards Tachykinin receptor 2 in CHO cells using [3H]-neurokinin A as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093088BDBM50093088(2-[1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-(...)
Affinity DataKi:  34nMAssay Description:Binding affinity towards Tachykinin receptor 2 in CHO cells using [3H]-neurokinin A as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093093BDBM50093093(CHEMBL76334 | 1-(3,5-Bis-trifluoromethyl-benzyloxy...)
Affinity DataKi:  122nMAssay Description:Binding affinity towards Tachykinin receptor 2 in CHO cells using [3H]-neurokinin A as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093093BDBM50093093(CHEMBL76334 | 1-(3,5-Bis-trifluoromethyl-benzyloxy...)
Affinity DataKi:  358nMAssay Description:Binding affinity towards Tachykinin receptor 2 in CHO cells using [3H]-neurokinin A as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093089BDBM50093089((S)-1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-d...)
Affinity DataKi:  397nMAssay Description:Binding affinity towards Tachykinin receptor 2 in CHO cells using [3H]-neurokinin A as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed