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Found 6 Enz. Inhib. hit(s) with all data for entry = 50010308
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093126((4-{(S)-2-Acetylamino-2-[1-((1R,2S)-2-carbamoyl-cy...)
Affinity DataIC50:  530nMAssay Description:Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093125((4-{(S)-2-Acetylamino-2-[1-((1R,2S)-2-carbamoyl-cy...)
Affinity DataIC50:  700nMAssay Description:Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093127((4-{(S)-2-Acetylamino-2-[1-((1R,2S)-2-carbamoyl-cy...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093129((4-{(S)-2-Acetylamino-2-[1-((1R,2S)-2-carbamoyl-cy...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093128((4-{(S)-2-Acetylamino-2-[1-((1R,2S)-2-carbamoyl-cy...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50093130((4-{(S)-2-Acetylamino-2-[1-((1R,2S)-2-carbamoyl-cy...)
Affinity DataIC50:  2.55E+4nMAssay Description:Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed