Compile Data Set for Download or QSAR
Report error Found 186 Enz. Inhib. hit(s) with all data for entry = 11199
TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475561BDBM475561(1-[6-Chloro-5-(4-chloro-phenylmethanesulfonyl)-1H-...)
Affinity DataIC50: 15.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475563BDBM475563(1-(6-Chloro-5-cyclohexylmethanesulfonyl-1H- | US10...)
Affinity DataIC50: 20nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475569BDBM475569(1-[6-Chloro-5-(2'-cyano-biphenyl-4-ylmethanesulfon...)
Affinity DataIC50: 20nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475567BDBM475567(1-[6-Chloro-5-(4-trifluoromethyl-phenylmethanesulf...)
Affinity DataIC50: 20nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475557BDBM475557(US10851083, Example 178 | 1-[6-Chloro-5-(4-methyl-...)
Affinity DataIC50: 20nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475479BDBM475479(1-[6-Chloro-5-(4-methoxy-phenylmethanesulfonyl)-1H...)
Affinity DataIC50: 20nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475485BDBM475485(1-(6-Methanesulfonyl-5-trifluoromethyl-1H- | US108...)
Affinity DataIC50: 25.1nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475549BDBM475549(1-(5-Benzenesulfonyl-6-trifluoromethyl-1H- | US108...)
Affinity DataIC50: 25.1nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475564BDBM475564(1-[6-Chloro-5-(3,4-dichloro-phenylmethanesulfonyl)...)
Affinity DataIC50: 25.1nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475562BDBM475562(1-[6-Chloro-5-(3-chloro-phenylmethanesulfonyl)-1H-...)
Affinity DataIC50: 25.1nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475568BDBM475568(1-[5-(2,4-Bis-trifluoromethyl-phenylmethanesulfony...)
Affinity DataIC50: 25.1nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475550BDBM475550(1-[5-(4-Methoxy-benzenesulfonyl)-6-trifluoromethyl...)
Affinity DataIC50: 25.1nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475401BDBM475401(1-{5-[3-(2-Chloro-benzyloxy)-phenyl]-1H-benzoimida...)
Affinity DataIC50: 25.1nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475543BDBM475543(1-(5-Ethylsulfonyl-6-trifluoromethoxy-1H-benzoimid...)
Affinity DataIC50: 25.1nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475542BDBM475542(1-(5-Ethylsulfonyl-6-trifluoromethyl-1H-benzoimida...)
Affinity DataIC50: 25.1nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475471BDBM475471(1-(5-Benzenesulfonyl-6-chloro-1H-benzoimidazol-2-y...)
Affinity DataIC50: 26.9nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475548BDBM475548(1-[5-(4-Methoxy-phenylsulfanyl)-6-trifluoromethyl-...)
Affinity DataIC50: 31.6nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475488BDBM475488(1-(6-Methanesulfonyl-5-trifluoromethoxy-1H- | US10...)
Affinity DataIC50: 31.6nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475428BDBM475428(1-(6-Chloro-5-nitro-1H-benzoimidazol-2-yl)-1H-pyra...)
Affinity DataIC50: 31.6nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475492BDBM475492(1-[6-(Propane-1-sulfonyl)-5-trifluoromethyl-1H- | ...)
Affinity DataIC50: 31.6nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475490BDBM475490(1-[5-Chloro-6-(propane-1-sulfonyl)-1H-benzoimidazo...)
Affinity DataIC50: 31.6nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475400BDBM475400(1-{5-[3-(3-Chloro-benzyloxy)-phenyl]-1H-benzoimida...)
Affinity DataIC50: 31.6nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475560BDBM475560(1-[6-Chloro-5-(2'-cyano-biphenyl-4-ylmethylsulfany...)
Affinity DataIC50: 31.6nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475494BDBM475494(1-[6-(Propane-1-sulfonyl)-5-trifluoromethoxy-1H- |...)
Affinity DataIC50: 31.6nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475565BDBM475565(1-[6-Chloro-5-(2,6-dichloro-phenylmethanesulfonyl)...)
Affinity DataIC50: 31.6nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475477BDBM475477(1-(6-Chloro-5-phenylmethanesulfonyl-1H- | US108510...)
Affinity DataIC50: 31.6nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475443BDBM475443(1-[5-(4-Chloro-phenoxy)-6-trifluoromethyl-1H- | US...)
Affinity DataIC50: 31.6nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475481BDBM475481(1-[6-Chloro-5-(2-chloro-phenylmethanesulfonyl)-1H-...)
Affinity DataIC50: 31.6nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475480BDBM475480(1-[6-Chloro-5-(4-fluoro-phenylmethanesulfonyl)-1H-...)
Affinity DataIC50: 31.6nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475484BDBM475484(1-(5-Chloro-6-ethanesulfonyl-1H-benzoimidazol-2-yl...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475547BDBM475547(1-(5-Phenylsulfanyl-6-trifluoromethyl-1H-benzoimid...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475482BDBM475482(1-[6-Chloro-5-(2-phenyl-ethanesulfonyl)-1H- | US10...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475514BDBM475514(1-(5,6-Bis-trifluoromethyl-1H-benzoimidazol-2-yl)-...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475487BDBM475487(1-(5-Chloro-6-methanesulfonyl-1H-benzoimidazol-2-y...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475493BDBM475493(1-[6-(Propane-2-sulfonyl)-5-trifluoromethoxy-1H- |...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475427BDBM475427(1-(6-Chloro-5-cyano-1H-benzoimidazol-2-yl)-1H- | U...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475491BDBM475491(1-[6-(Propane-2-sulfonyl)-5-trifluoromethyl-1H- | ...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475402BDBM475402(1-{5-[3-(4-Chloro-benzyloxy)-phenyl]-1H-benzoimida...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475440BDBM475440(1-[5-(4-Chloro-phenoxy)-6-trifluoromethoxy-1H- | U...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475439BDBM475439(1-[6-Chloro-5-(4-chloro-phenoxy)-1H-benzoimidazol-...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475535BDBM475535(1-[6-Chloro-5-(4-trifluoromethoxy-phenoxy)-1H- | U...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475438BDBM475438(1-[5-(3,4-Dichloro-phenoxy)-6-trifluoromethyl-1H- ...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475470BDBM475470(1-[6-Chloro-5-(toluene-3-sulfonyl)-1H-benzoimidazo...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475476BDBM475476(1-[6-Chloro-5-(3-methoxy-benzenesulfonyl)-1H- | US...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475545BDBM475545(1-(6-Fluoro-5-propylsulfonyl-1H-benzoimidazol-2-yl...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475544BDBM475544(1-(5-Ethylsulfonyl-6-fluoro-1H-benzoimidazol-2-yl)...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475574BDBM475574(1-(6-Chloro-5-phenylsulfamoyl-1H-benzoimidazol-2-y...)
Affinity DataIC50: 39.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475403BDBM475403(1-[5-(3-Benzyloxy-phenyl)-1H-benzoimidazol-2-yl]-1...)
Affinity DataIC50: 50.1nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475546BDBM475546(1-(6-Fluoro-5-isopropylsulfonyl-1H-benzoimidazol-2...)
Affinity DataIC50: 50.1nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475489BDBM475489(1-[5-Chloro-6-(propane-2-sulfonyl)-1H-benzoimidazo...)
Affinity DataIC50: 50.1nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

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