Compile Data Set for Download or QSAR
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Found 29 Enz. Inhib. hit(s) with all data for entry = 50011205
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103722(CHEMBL3084802 | N-{4-[5-Amino-1-(3-trifluoromethyl...)
Affinity DataIC50:  10nMAssay Description:Binding affinity of the compound towards human neuropeptide Y receptor type 5 in HEK 293 cell line by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103712(CHEMBL430414 | N-[4-(5-Amino-1-p-tolyl-1H-pyrazol-...)
Affinity DataIC50:  15nMAssay Description:Binding affinity of the compound towards human neuropeptide Y receptor type 5 in HEK 293 cell line by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103733(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50:  80nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103721(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50:  150nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103720(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50:  197nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103718(5-Methyl-1-m-tolyl-1H-pyrazole-3-carboxylic acid (...)
Affinity DataIC50:  218nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103742(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50:  232nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103731(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50:  233nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103727(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50:  267nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103737(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50:  292nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103724(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50:  356nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103736(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50:  359nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103741(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50:  431nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103726(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50:  520nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103744(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50:  573nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103735(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50:  622nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103730(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50:  670nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103723(5-Methyl-1-phenyl-1H-pyrazole-3-carboxylic acid (3...)
Affinity DataIC50:  759nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103729(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50:  763nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103745(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50:  800nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103743(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103740(5-Methyl-1-pyridin-2-yl-1H-pyrazole-3-carboxylic a...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103719(1-Benzyl-5-methyl-1H-pyrazole-3-carboxylic acid (3...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103739(1-(3-Methoxy-phenyl)-5-methyl-1H-pyrazole-3-carbox...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103725(5-Methyl-1-(2-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103728(5-Methyl-1-(4-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103734(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103732(5-Methyl-1-thiophen-2-yl-1H-pyrazole-3-carboxylic ...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103738(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed