Compile Data Set for Download or QSAR
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Found 25 Enz. Inhib. hit(s) with all data for entry = 50035151
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50103880(Benzoic acid 8-allyl-2-oxo-2H-chromen-7-yl ester |...)
Affinity DataIC50:  490nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50103880(Benzoic acid 8-allyl-2-oxo-2H-chromen-7-yl ester |...)
Affinity DataIC50:  490nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50103879(CHEMBL312466 | Phenyl-carbamic acid 8-allyl-2-oxo-...)
Affinity DataIC50:  620nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50103879(CHEMBL312466 | Phenyl-carbamic acid 8-allyl-2-oxo-...)
Affinity DataIC50:  620nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50103878(Acetic acid 8-allyl-2-oxo-2H-chromen-7-yl ester | ...)
Affinity DataIC50:  820nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50103878(Acetic acid 8-allyl-2-oxo-2H-chromen-7-yl ester | ...)
Affinity DataIC50:  820nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50103881(8-Allyl-7-hydroxy-chromen-2-one | CHEMBL77650)
Affinity DataIC50:  990nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50103881(8-Allyl-7-hydroxy-chromen-2-one | CHEMBL77650)
Affinity DataIC50:  990nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50103876(7-(1,1-Dimethyl-allyloxy)-chromen-2-one | CHEMBL31...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50103876(7-(1,1-Dimethyl-allyloxy)-chromen-2-one | CHEMBL31...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50103877(6-Allyl-7-hydroxy-chromen-2-one | CHEMBL76373)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50103877(6-Allyl-7-hydroxy-chromen-2-one | CHEMBL76373)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50218783(CHEMBL308610)
Affinity DataIC50: >1.36E+4nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50218785(CHEMBL76687)
Affinity DataIC50: >1.49E+4nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50218784(CHEMBL80175)
Affinity DataIC50: >1.84E+4nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50103875(8-Allyl-7-(1,1-dimethyl-allyloxy)-chromen-2-one | ...)
Affinity DataIC50:  5.03E+4nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50103875(8-Allyl-7-(1,1-dimethyl-allyloxy)-chromen-2-one | ...)
Affinity DataIC50:  5.03E+4nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50218787(CHEMBL77167)
Affinity DataIC50: >7.74E+4nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50218789(CHEMBL77117)
Affinity DataIC50: >8.12E+4nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50218788(CHEMBL77649)
Affinity DataIC50: >8.76E+4nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50366103(CHEMBL432745)
Affinity DataIC50: >9.89E+4nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50143207(CHEMBL308819)
Affinity DataIC50: >9.99E+4nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50174558(7-hydroxy-2H-1-benzopyran-2-one | 7-hydroxy-2H-chr...)
Affinity DataIC50: >1.23E+5nMAssay Description:Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed