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Found 6 Enz. Inhib. hit(s) with all data for entry = 50011250
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104208(8-[5-((R)-3-Dimethylamino-pyrrolidine-1-sulfonyl)-...)
Affinity DataIC50:  0.310nMAssay Description:Inhibition of PDE5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104206(5-(3-Chloro-4-methoxy-benzylamino)-8-[5-((R)-3-dim...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of PDE5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of PDE5 from human plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104204(8-[5-((R)-3-Dimethylamino-pyrrolidine-1-sulfonyl)-...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of PDE5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104207(8-[5-((R)-3-Dimethylamino-pyrrolidine-1-sulfonyl)-...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of PDE5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104205(5-Chloro-8-[5-((R)-3-dimethylamino-pyrrolidine-1-s...)
Affinity DataIC50:  13nMAssay Description:Inhibition of PDE5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed