Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 327
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Stockholm University

LigandPNGBDBM587((2R,3R,4R,5R)-3,4-dihydroxy-N,N'-bis[(1S)-2-methyl...)
Affinity DataKi:  0.400nM ΔG°:  -54.5kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Stockholm University

LigandPNGBDBM358(symmetric/asymmetric inhibitor 2 | (2R,3R,4R,5R)-2...)
Affinity DataKi:  0.600nM ΔG°:  -53.5kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Stockholm University

LigandPNGBDBM348(1-Valine Methylamide deriv. 1 | Diol-Based HIV-1 p...)
Affinity DataKi:  0.800nM ΔG°:  -52.8kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Stockholm University

LigandPNGBDBM585((2R,3R,4R,5R)-3,4-dihydroxy-N,N'-bis[(1S,2R)-2-hyd...)
Affinity DataKi:  1.10nM ΔG°:  -52.0kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Stockholm University

LigandPNGBDBM584(N1,N6 -Bis[(2R)-hydroxy-(1S)-indanyl]-(2R,3R,4S,5R...)
Affinity DataKi:  28nM ΔG°:  -43.8kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Stockholm University

LigandPNGBDBM586(N ,N6 -Bis[(1S)-2-methyl-1-(methylcarbamoyl)propyl...)
Affinity DataKi:  112nM ΔG°:  -40.3kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2004
Entry Details Article
PubMed