Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 848
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6655BDBM6655(3-(9-oxo-9H-fluoren-4-yl)-1-pyridin-2-ylurea | N-(...)
Affinity DataIC50: 100nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6656BDBM6656(3-1H-indazol-6-yl-1-pyridin-2-ylurea | N-(1H-Indaz...)
Affinity DataIC50: 670nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6657BDBM6657(3-pyridin-2-yl-1-quinolin-5-ylurea | N-Pyridin-2-y...)
Affinity DataIC50: 2.40E+3nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6658BDBM6658(N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-4-yl)-N -pyri...)
Affinity DataIC50: 3.60E+3nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6654BDBM6654(3-(7-hydroxynaphthalen-1-yl)-1-pyridin-2-ylurea | ...)
Affinity DataIC50: 7.60E+3nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6641BDBM6641((5E)-5-[(2-methyl-1H-indol-3-yl)methylidene]-2-sul...)
Affinity DataIC50: 1.40E+4nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6645BDBM6645(4-{[(2-amino-4-hydroxypteridin-6-yl)methyl]amino}b...)
Affinity DataIC50: 1.60E+4nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6649BDBM6649(1-(7-hydroxynaphthalen-1-yl)-3-1,3-thiazol-2-ylure...)
Affinity DataIC50: 2.30E+4nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6643BDBM6643(2-amino-4-(2H-1,3-benzodioxol-5-yl)-6-methoxypyrid...)
Affinity DataIC50: 3.60E+4nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6636BDBM6636(3-(3-chlorophenyl)-1-[2-(dimethylamino)quinolin-4-...)
Affinity DataIC50: 3.60E+4nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6638BDBM6638(1-(5-hydroxynaphthalen-1-yl)-3-[4-(methylsulfanyl)...)
Affinity DataIC50: 4.00E+4nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6634BDBM6634(3-(5-chloro-2-methylphenyl)-1-(7-hydroxynaphthalen...)
Affinity DataIC50: 4.40E+4nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6637BDBM6637(1,3-bis(quinolin-6-yl)urea | Diarylurea 4)
Affinity DataIC50: 7.70E+4nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6635BDBM6635(1-[2-(dimethylamino)quinolin-4-yl]-3-phenylurea | ...)
Affinity DataIC50: 9.00E+4nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6640BDBM6640(5-[(2-hydroxynaphthalen-1-yl)methylidene]-2-sulfan...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6659BDBM6659(1-phenyl-3-pyridin-2-ylurea | cid_221427 | N-Pheny...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6660BDBM6660(1-benzyl-3-pyridin-2-ylurea | N-Benzyl-N -pyridin-...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6661BDBM6661(N-Cyclohexyl-N -pyridin-2-ylurea | 1-cyclohexyl-3-...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6648BDBM6648(N-(7-Hydroxy-1-naphthyl)-N -pyridin-4-ylurea | 3-(...)
Affinity DataIC50: 1.10E+5nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6646BDBM6646(3-(7-hydroxynaphthalen-1-yl)-1-phenylurea | N-(7-H...)
Affinity DataIC50: 1.20E+5nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6652BDBM6652(3-cyclopentyl-1-(7-hydroxynaphthalen-1-yl)urea | N...)
Affinity DataIC50: 1.50E+5nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6644BDBM6644(Pteridine deriv. 11 | 6-phenylpteridine-2,4,7-tria...)
Affinity DataIC50: 2.10E+5nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6651BDBM6651(N-(7-Hydroxy-1-naphthyl)-N -isopropylurea | 1-(7-h...)
Affinity DataIC50: 2.20E+5nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6647BDBM6647(3-(7-hydroxynaphthalen-1-yl)-1-pyridin-3-ylurea | ...)
Affinity DataIC50: 3.40E+5nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6639BDBM6639(5-(2H-1,3-benzodioxol-5-ylmethylidene)-1,3-diazina...)
Affinity DataIC50: 3.50E+5nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6650BDBM6650(CHEMBL139989 | N-Benzyl-N -(7-hydroxy-1-naphthyl)u...)
Affinity DataIC50: 4.10E+5nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6642BDBM6642(6-(6-chloro-2H-chromen-3-yl)-1,3,5-triazine-2,4-di...)
Affinity DataIC50: 4.50E+5nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandChemical structure of BindingDB Monomer ID 6653BDBM6653(N-(7-hydroxynaphthalen-1-yl)-2-phenylacetamide | N...)
Affinity DataIC50: 1.00E+6nMT: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed