Compile Data Set for Download or QSAR
maximum 50k data
Found 61 Enz. Inhib. hit(s) with all data for entry = 50011642
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108858(CHEMBL347459 | {1-[2-Oxo-1-phenethyl-3-(3-phenyl-p...)
Affinity DataKi:  0.900nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108858(CHEMBL347459 | {1-[2-Oxo-1-phenethyl-3-(3-phenyl-p...)
Affinity DataKi:  0.900nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108847(CHEMBL162474 | benzyl (S)-4-methyl-1-oxo-1-((S)-3-...)
Affinity DataKi:  1nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108849(CHEMBL321974 | {(S)-3-Methyl-1-[(S)-2-oxo-1-phenet...)
Affinity DataKi:  1.10nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108857(CHEMBL160000 | [1-(1-Benzyl-3-tert-butylsulfanyl-2...)
Affinity DataKi:  1.30nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108846(CHEMBL161038 | [1-(3-tert-Butylsulfanyl-2-oxo-1-ph...)
Affinity DataKi:  1.40nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50108840(3-[3-(2-Benzyloxycarbonylamino-3-phenyl-propionyla...)
Affinity DataKi:  1.5nMAssay Description:Inhibitory activity of the compound against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50108862(CHEMBL161651 | [1-(1-Benzyl-3-tert-butylsulfanyl-2...)
Affinity DataKi:  1.70nMAssay Description:Inhibitory activity of the compound against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108856(CHEMBL103238 | benzyl (S)-1-oxo-1-((S)-3-oxo-1-phe...)
Affinity DataKi:  2nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108855(CHEMBL352168 | [1-(3-tert-Butylsulfanyl-2-oxo-1-ph...)
Affinity DataKi:  2nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108862(CHEMBL161651 | [1-(1-Benzyl-3-tert-butylsulfanyl-2...)
Affinity DataKi:  2.5nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50108856(CHEMBL103238 | benzyl (S)-1-oxo-1-((S)-3-oxo-1-phe...)
Affinity DataKi:  2.80nMAssay Description:Inhibitory activity of the compound against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108840(3-[3-(2-Benzyloxycarbonylamino-3-phenyl-propionyla...)
Affinity DataKi:  2.90nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108852(CHEMBL100849 | [(S)-1-((S)-1-Benzyl-2-oxo-3-phenet...)
Affinity DataKi:  4.20nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108854(CHEMBL158806 | [1-(1-Benzyl-3-tert-butylsulfanyl-2...)
Affinity DataKi:  4.60nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108863(CHEMBL162695 | [1-(1-Benzyl-3-isopropylsulfanyl-2-...)
Affinity DataKi:  4.60nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50108847(CHEMBL162474 | benzyl (S)-4-methyl-1-oxo-1-((S)-3-...)
Affinity DataKi:  4.70nMAssay Description:Inhibitory activity of the compound against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108874(CHEMBL351045 | [1-(1-Benzyl-3-tert-butylsulfanyl-2...)
Affinity DataKi:  4.80nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108866((1-{1-Benzyl-3-[1-(2,2-dimethyl-propyl)-1,3,3-trim...)
Affinity DataKi:  5nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108850(CHEMBL158567 | {1-[1-Benzyl-2-oxo-3-(3-phenyl-prop...)
Affinity DataKi:  5.5nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108873(CHEMBL161424 | [1-(1-Benzyl-3-sec-butylsulfanyl-2-...)
Affinity DataKi:  5.80nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108841(CHEMBL161508 | [1-(1-Benzyl-3-cyclohexylsulfanyl-2...)
Affinity DataKi:  7.5nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50375354(CHEMBL258808)
Affinity DataKi:  7.80nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50108857(CHEMBL160000 | [1-(1-Benzyl-3-tert-butylsulfanyl-2...)
Affinity DataKi:  7.90nMAssay Description:Inhibitory activity of the compound against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108864(3-[3-(2-Benzyloxycarbonylamino-4-methyl-pentanoyla...)
Affinity DataKi:  8nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50108846(CHEMBL161038 | [1-(3-tert-Butylsulfanyl-2-oxo-1-ph...)
Affinity DataKi:  9.60nMAssay Description:Inhibitory activity of the compound against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108861(CHEMBL348117 | benzyl (S)-1-oxo-1-((S)-3-oxo-1-phe...)
Affinity DataKi:  10.4nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108860(CHEMBL348163 | [1-(1-Benzyl-3-tert-butylsulfanyl-2...)
Affinity DataKi:  13.8nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108845(CHEMBL436227 | [1-(1-Benzyl-3-tert-butylsulfanyl-2...)
Affinity DataKi:  14.1nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108868(CHEMBL351721 | [1-(1-Benzyl-3-methylcarbamoylmethy...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108838(CHEMBL346190 | benzyl (S)-1-((S)-4-(4-tert-butylbe...)
Affinity DataKi:  22nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108867(3-{2-Oxo-4-phenyl-3-[3-phenyl-2-(pyridin-3-ylmetho...)
Affinity DataKi:  22.7nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50108845(CHEMBL436227 | [1-(1-Benzyl-3-tert-butylsulfanyl-2...)
Affinity DataKi:  28.8nMAssay Description:Inhibitory activity of the compound against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50108858(CHEMBL347459 | {1-[2-Oxo-1-phenethyl-3-(3-phenyl-p...)
Affinity DataKi:  28.8nMAssay Description:Inhibitory activity of the compound against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108875(CHEMBL157806 | benzyl (S)-1-((S)-4-(isopentylthio)...)
Affinity DataKi:  30.1nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108839(3-{2-Oxo-4-phenyl-3-[3-phenyl-2-(pyridin-2-ylmetho...)
Affinity DataKi:  30.4nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108848(CHEMBL348300 | [3-(2-Benzyloxycarbonylamino-3-phen...)
Affinity DataKi:  31.2nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108865(CHEMBL263133 | benzyl (S)-1-((S)-4-(4-methoxybenzy...)
Affinity DataKi:  32.4nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108876(CHEMBL352896 | benzyl (S)-1-((S)-4-(2-acetamidoeth...)
Affinity DataKi:  34.3nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108870(CHEMBL159089 | [1-(1-Benzyl-3-cyclopentylsulfanyl-...)
Affinity DataKi:  34.3nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108844(2-[3-(2-Benzyloxycarbonylamino-3-phenyl-propionyla...)
Affinity DataKi:  37nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50108840(3-[3-(2-Benzyloxycarbonylamino-3-phenyl-propionyla...)
Affinity DataKi:  42.7nMAssay Description:Inhibitory activity of the compound against human Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50108855(CHEMBL352168 | [1-(3-tert-Butylsulfanyl-2-oxo-1-ph...)
Affinity DataKi:  44nMAssay Description:Inhibitory activity of the compound against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108853(CHEMBL321988 | [(S)-1-((S)-1-Benzyl-3-benzylsulfan...)
Affinity DataKi:  44nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50108862(CHEMBL161651 | [1-(1-Benzyl-3-tert-butylsulfanyl-2...)
Affinity DataKi:  45nMAssay Description:Inhibitory activity of the compound against human Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50108856(CHEMBL103238 | benzyl (S)-1-oxo-1-((S)-3-oxo-1-phe...)
Affinity DataKi:  45.4nMAssay Description:Inhibitory activity of the compound against human Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108871(CHEMBL162250 | Morpholine-4-carboxylic acid [1-(1-...)
Affinity DataKi:  54.6nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108872(3-(3-{2-[(Morpholine-4-carbonyl)-amino]-3-phenyl-p...)
Affinity DataKi:  59.1nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108842(CHEMBL161116 | Morpholine-4-carboxylic acid [1-(1-...)
Affinity DataKi:  59.7nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of California

Curated by ChEMBL
LigandPNGBDBM50108869(3-(3-{4-Methyl-2-[(morpholine-4-carbonyl)-amino]-p...)
Affinity DataKi:  69.6nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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