Compile Data Set for Download or QSAR
maximum 50k data
Found 13 Enz. Inhib. hit(s) with all data for entry = 50011759
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50110208(4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1...)
Affinity DataIC50:  94nMAssay Description:Inhibition of Activin like receptor kinase 5, TGF beta type I receptorMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50110205(4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1...)
Affinity DataIC50:  170nMAssay Description:Inhibition of Activin like receptor kinase 5, TGF beta type I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50110202((4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-...)
Affinity DataIC50:  260nMAssay Description:Inhibition of Activin like receptor kinase 5, TGF beta type I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50110200(4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-imidazol-...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Activin like receptor kinase 5, TGF beta type I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50110206(3-(benzo[d][1,3]dioxol-5-yl)-2-(pyridin-2-yl)-6,7-...)
Affinity DataIC50:  460nMAssay Description:Inhibition of Activin like receptor kinase 5, TGF beta type I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50110199(4-(4-(4-fluorophenyl)-5-(pyridin-2-yl)-1H-imidazol...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Activin like receptor kinase 5, TGF beta type I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50110201(5-(4-Fluoro-phenyl)-6-pyridin-2-yl-2,3-dihydro-imi...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Activin like receptor kinase 5, TGF beta type I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50110197(4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1...)
Affinity DataIC50:  2.95E+3nMAssay Description:Inhibition of Activin like receptor kinase 5, TGF beta type I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50110198(3-(4-Methoxy-phenyl)-2-pyridin-2-yl-6,7-dihydro-5H...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of Activin like receptor kinase 5, TGF beta type I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50110203(3-(4-Fluoro-phenyl)-2-pyridin-2-yl-6,7-dihydro-5H-...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of Activin like receptor kinase 5, TGF beta type I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of Activin like receptor kinase 5, TGF beta type I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50110207(3-(4-Fluoro-phenyl)-2-pyridin-3-yl-6,7-dihydro-5H-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Activin like receptor kinase 5, TGF beta type I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50110204(5-(4-Fluoro-phenyl)-6-pyridin-4-yl-2,3-dihydro-imi...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Activin like receptor kinase 5, TGF beta type I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed