Compile Data Set for Download or QSAR
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Found 17 Enz. Inhib. hit(s) with all data for entry = 50048524
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50114418(8-Methoxy-2-trifluoromethyl-quinoline-5-carboxylic...)
Affinity DataIC50:  7nMAssay Description:Inhibition of rolipram binding to PDE4 of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219830(CHEMBL42387)
Affinity DataIC50:  35nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219830(CHEMBL42387)
Affinity DataIC50:  38nMAssay Description:Inhibition of rolipram binding to PDE4 of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50114418(8-Methoxy-2-trifluoromethyl-quinoline-5-carboxylic...)
Affinity DataIC50:  51nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219829(CHEMBL288195)
Affinity DataIC50:  58nMAssay Description:Inhibition of rolipram binding to PDE4 of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219270(3,5-Dichloro-4-[(8-methoxy-2-trifluoromethyl-quino...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Phosphodiesterase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219270(3,5-Dichloro-4-[(8-methoxy-2-trifluoromethyl-quino...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219826(CHEMBL607242)
Affinity DataIC50:  60nMAssay Description:Inhibition of rolipram binding to PDE4 of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219826(CHEMBL607242)
Affinity DataIC50:  70nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219827(CHEMBL42479)
Affinity DataIC50:  110nMAssay Description:Inhibition of rolipram binding to PDE4 of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219829(CHEMBL288195)
Affinity DataIC50:  120nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219828(CHEMBL607241)
Affinity DataIC50:  150nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219270(3,5-Dichloro-4-[(8-methoxy-2-trifluoromethyl-quino...)
Affinity DataIC50:  150nMAssay Description:Inhibition of rolipram binding to PDE4 of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219831(CHEMBL607240)
Affinity DataIC50:  240nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219831(CHEMBL607240)
Affinity DataIC50:  370nMAssay Description:Inhibition of rolipram binding to PDE4 of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219828(CHEMBL607241)
Affinity DataIC50:  380nMAssay Description:Inhibition of rolipram binding to PDE4 of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50219827(CHEMBL42479)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed