Compile Data Set for Download or QSAR
Report error Found 141 Enz. Inhib. hit(s) with all data for entry = 12079
TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676804BDBM676804(US20240166660, Compound B1)
Affinity DataIC50: 3nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676897BDBM676897(US20240166660, Compound B94 | US20240166660, Compo...)
Affinity DataIC50: 3.26nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676844BDBM676844(US20240166660, Compound B41)
Affinity DataIC50: 3.80nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676832BDBM676832(US20240166660, Compound B29)
Affinity DataIC50: 4.51nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676814BDBM676814(US20240166660, Compound B11 | US20240166660, Compo...)
Affinity DataIC50: 4.60nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676869BDBM676869(US20240166660, Compound B66 | US20240166660, Compo...)
Affinity DataIC50: 4.60nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676897BDBM676897(US20240166660, Compound B94 | US20240166660, Compo...)
Affinity DataIC50: 4.63nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676807BDBM676807(US20240166660, Compound B4)
Affinity DataIC50: 4.70nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676790BDBM676790(US20240166660, Compound A21)
Affinity DataIC50: 5nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676885BDBM676885(US20240166660, Compound B82)
Affinity DataIC50: 6.20nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676806BDBM676806(US20240166660, Compound B3)
Affinity DataIC50: 6.5nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676903BDBM676903(US20240166660, Compound B100 | US20240166660, Comp...)
Affinity DataIC50: 6.53nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676906BDBM676906(US20240166660, Compound B103)
Affinity DataIC50: 6.95nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676814BDBM676814(US20240166660, Compound B11 | US20240166660, Compo...)
Affinity DataIC50: 7.81nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676808BDBM676808(US20240166660, Compound B5)
Affinity DataIC50: 7.90nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676840BDBM676840(US20240166660, Compound B37)
Affinity DataIC50: 8nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676907BDBM676907(US20240166660, Compound B104 | US20240166660, Comp...)
Affinity DataIC50: 8.16nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676838BDBM676838(US20240166660, Compound B35)
Affinity DataIC50: 8.40nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676798BDBM676798(US20240166660, Compound A29)
Affinity DataIC50: 9.30nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676869BDBM676869(US20240166660, Compound B66 | US20240166660, Compo...)
Affinity DataIC50: 9.30nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676897BDBM676897(US20240166660, Compound B94 | US20240166660, Compo...)
Affinity DataIC50: 9.54nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676833BDBM676833(US20240166660, Compound B30)
Affinity DataIC50: 9.60nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676795BDBM676795(US20240166660, Compound A26)
Affinity DataIC50: 9.90nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676896BDBM676896(US20240166660, Compound B93)
Affinity DataIC50: 11nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676897BDBM676897(US20240166660, Compound B94 | US20240166660, Compo...)
Affinity DataIC50: 11.5nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676881BDBM676881(US20240166660, Compound B78)
Affinity DataIC50: 12nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676801BDBM676801(US20240166660, Compound A32 | US20240166660, Compo...)
Affinity DataIC50: 12nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676846BDBM676846(US20240166660, Compound B43)
Affinity DataIC50: 13nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676843BDBM676843(US20240166660, Compound B40)
Affinity DataIC50: 14nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676851BDBM676851(US20240166660, Compound B48)
Affinity DataIC50: 14nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676789BDBM676789(US20240166660, Compound A20)
Affinity DataIC50: 14.9nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676893BDBM676893(US20240166660, Compound B90 | US20240166660, Compo...)
Affinity DataIC50: 15nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676794BDBM676794(US20240166660, Compound A25)
Affinity DataIC50: 15.5nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676823BDBM676823(US20240166660, Compound B20)
Affinity DataIC50: 16nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676903BDBM676903(US20240166660, Compound B100 | US20240166660, Comp...)
Affinity DataIC50: 18nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676889BDBM676889(US20240166660, Compound B86)
Affinity DataIC50: 19nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676850BDBM676850(US20240166660, Compound B47)
Affinity DataIC50: 25nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676856BDBM676856(US20240166660, Compound B53)
Affinity DataIC50: 28nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676868BDBM676868(US20240166660, Compound B65)
Affinity DataIC50: 30nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676786BDBM676786(US20240166660, Compound A17)
Affinity DataIC50: 31.7nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676809BDBM676809(US20240166660, Compound B6)
Affinity DataIC50: 34nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676873BDBM676873(US20240166660, Compound B70)
Affinity DataIC50: 35nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676893BDBM676893(US20240166660, Compound B90 | US20240166660, Compo...)
Affinity DataIC50: 37nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676787BDBM676787(US20240166660, Compound A18)
Affinity DataIC50: 37.8nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676857BDBM676857(US20240166660, Compound B54)
Affinity DataIC50: 40nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676845BDBM676845(US20240166660, Compound B42)
Affinity DataIC50: 43nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676776BDBM676776(US20240166660, Compound A7)
Affinity DataIC50: 43.1nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676878BDBM676878(US20240166660, Compound B75)
Affinity DataIC50: 44nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676839BDBM676839(US20240166660, Compound B36)
Affinity DataIC50: 47nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetGTPase KRas [G12C,C51S,C80L,C118S](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 676884BDBM676884(US20240166660, Compound B81)
Affinity DataIC50: 48nMAssay Description:The KRAS (aa 1-169) G12C, C51S, C80L, C118S with a His-tag was expressed, purified and loaded with GDP in house. All protein and substrate solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

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