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Found 39 Enz. Inhib. hit(s) with all data for entry = 50012212
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116208(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50029275(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116204(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116209(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116210(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  12nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116206((S)-1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethy...)
Affinity DataKi:  12nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116207(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116210(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116206((S)-1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethy...)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116207(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50029275(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116203(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  23nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116208(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  25nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116203(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  40nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116209(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  47nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116205(1-(5-Bromo-thiophen-2-ylmethyl)-4-(2-methoxy-pheny...)
Affinity DataKi:  92nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116204(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  92nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116205(1-(5-Bromo-thiophen-2-ylmethyl)-4-(2-methoxy-pheny...)
Affinity DataKi:  128nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116202(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  130nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116201(CHEMBL302495 | {5-[4-(2-Methoxy-phenyl)-piperazin-...)
Affinity DataKi:  138nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116201(CHEMBL302495 | {5-[4-(2-Methoxy-phenyl)-piperazin-...)
Affinity DataKi:  202nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116208(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  259nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116212(5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-thio...)
Affinity DataKi:  262nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116200(CHEMBL303485 | {5-[4-(2-Propoxy-phenyl)-piperazin-...)
Affinity DataKi:  331nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116200(CHEMBL303485 | {5-[4-(2-Propoxy-phenyl)-piperazin-...)
Affinity DataKi:  339nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1D adrenergic receptor expressed in COS cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116204(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  384nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50029275(1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl...)
Affinity DataKi:  413nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116202(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  419nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116212(5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-thio...)
Affinity DataKi:  578nMAssay Description:Displacement of [125I]-HEAT from COS cell membranes expressing human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116206((S)-1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethy...)
Affinity DataKi:  592nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116209(1-{5-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  615nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116205(1-(5-Bromo-thiophen-2-ylmethyl)-4-(2-methoxy-pheny...)
Affinity DataKi:  757nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116201(CHEMBL302495 | {5-[4-(2-Methoxy-phenyl)-piperazin-...)
Affinity DataKi:  1.06E+3nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116212(5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-thio...)
Affinity DataKi:  1.88E+3nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116202(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi:  2.57E+3nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116210(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116207(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116200(CHEMBL303485 | {5-[4-(2-Propoxy-phenyl)-piperazin-...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50116203(1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-t...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]-HEAT from COS cells membranes expressing human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed