Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 50012448
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50118955(CHEMBL94678 | Compound K-252a(epi))
Affinity DataIC50:  1.20nMAssay Description:Inhibition of nerve growth factor receptor, trkAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM6760((+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,1...)
Affinity DataIC50:  13nMAssay Description:Inhibition of nerve growth factor receptor, trkAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50118955(CHEMBL94678 | Compound K-252a(epi))
Affinity DataIC50:  19nMAssay Description:Inhibition of VEGF-receptor 2 (KDR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM6760((+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,1...)
Affinity DataIC50:  22nMAssay Description:Inhibition of Myosin light chain kinase 1 (MLCK1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50118955(CHEMBL94678 | Compound K-252a(epi))
Affinity DataIC50:  25nMAssay Description:Inhibition of Myosin light chain kinase 1 (MLCK1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM6760((+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,1...)
Affinity DataIC50:  43nMAssay Description:Inhibition of VEGF-receptor 2 (KDR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed