Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50012522
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50113224((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-phenyl-oxazol-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50116132((3-Methoxy-4-oxazol-5-yl-phenyl)-(4-methoxy-6-phen...)
Affinity DataIC50: 41nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120007((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-phenyl-[1,3,4]...)
Affinity DataIC50: 44nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50112573(N-(3-Methoxy-4-oxazol-5-yl-phenyl)-2-oxo-3-phenyl-...)
Affinity DataIC50: 52nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119999((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-phenyl-[1,2,4]...)
Affinity DataIC50: 59nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120001((3-Methoxy-4-oxazol-5-yl-phenyl)-(4-methoxy-6-phen...)
Affinity DataIC50: 110nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120006((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-phenyl-4,5-dih...)
Affinity DataIC50: 110nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120005((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-phenyl-isoxazo...)
Affinity DataIC50: 120nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50116129(N*3*-(3-Methoxy-4-oxazol-5-yl-phenyl)-1-phenyl-1H-...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120000((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-phenyl-4H-[1,2...)
Affinity DataIC50: 190nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120004((3-Methoxy-4-oxazol-5-yl-phenyl)-(4-phenyl-thiazol...)
Affinity DataIC50: 300nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120002((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-phenyl-[1,3,4]...)
Affinity DataIC50: 330nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50120003((3-Methoxy-4-oxazol-5-yl-phenyl)-(2-phenyl-thiazol...)
Affinity DataIC50: 760nMAssay Description:Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed