TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Concentration of the compound required to inhibit Human alpha-thrombin was determinedMore data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.00800nMAssay Description:Concentration of the compound required to inhibit Trypsin was determinedMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.00800nMAssay Description:Concentration of the compound required to inhibit thrombin was determinedMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Concentration of the compound required to inhibit thrombin was determinedMore data for this Ligand-Target Pair
TargetSerine protease 1(Bos taurus (bovine))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0450nMAssay Description:Concentration of the compound required to inhibit Trypsin was determinedMore data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Concentration of the compound required to inhibit Plasmin was determinedMore data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Concentration of the compound required to inhibit tissue-type plasminogen activator (t-PA) was determinedMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Concentration of the compound required to inhibit Coagulation factor X was determinedMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Concentration of the compound required to inhibit Human alpha-thrombin was determinedMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Concentration of the compound required to inhibit Coagulation factor X was determinedMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Concentration of the compound required to inhibit Human alpha-thrombin was determinedMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Concentration of the compound required to inhibit Human alpha-thrombin was determinedMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Concentration of the compound required to inhibit Human alpha-thrombin was determinedMore data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Concentration of the compound required to inhibit Plasmin was determinedMore data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Concentration of the compound required to inhibit Tissue-type plasminogen activator (t-PA) was determinedMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Concentration of the compound required to inhibit Human alpha-thrombin was determinedMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Concentration of the compound required to inhibit Human alpha-thrombin was determinedMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Concentration of the compound required to inhibit Human alpha-thrombin was determinedMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibitory constant of thrombin catalytic activity of the compound was determinedMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Concentration of the compound required to inhibit Human alpha-thrombin was determinedMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.30E+5nMAssay Description:Concentration of the compound required to inhibit Human alpha-thrombin was determinedMore data for this Ligand-Target Pair