Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50012800
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122900BDBM50122900(4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{1...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110122BDBM50110122((S)-4-((S)-2-Acetylamino-3-carboxy-propionylamino)...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122902BDBM50122902(4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{1...)
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122897BDBM50122897(4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{1...)
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110125BDBM50110125(2-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122892BDBM50122892(4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{1...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122898BDBM50122898(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-(1...)
Affinity DataIC50: 210nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122907BDBM50122907(4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{1...)
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122895BDBM50122895(3-[2-(2-tert-Butoxycarbonylamino-3-methyl-butyryla...)
Affinity DataIC50: 460nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122891BDBM50122891(4-(2-{2-[2-(4-Carboxy-2-isobutoxycarbonylamino-but...)
Affinity DataKi:  600nMAssay Description:Binding affinity for enzyme NS3 protease wild-typeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122887BDBM50122887(4-(2-{2-[2-(4-Carboxy-2-isobutoxycarbonylamino-but...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122891BDBM50122891(4-(2-{2-[2-(4-Carboxy-2-isobutoxycarbonylamino-but...)
Affinity DataKi:  900nMAssay Description:Binding affinity for enzyme K136RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122891BDBM50122891(4-(2-{2-[2-(4-Carboxy-2-isobutoxycarbonylamino-but...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity for enzyme K136MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122884BDBM50122884(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-(1...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122903BDBM50122903((5R,8S,11S,14S,17S,20S)-20-acetamido-14-benzhydryl...)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122899BDBM50122899(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-(1...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122893BDBM50122893(4-(2-{2-[2-(4-Carboxy-2-isobutoxycarbonylamino-but...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122883BDBM50122883(3-Chloro-4-(2-{4,4-difluoro-2-[2-(2-isobutoxycarbo...)
Affinity DataKi:  2.10E+3nMAssay Description:Binding affinity for wild type NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122883BDBM50122883(3-Chloro-4-(2-{4,4-difluoro-2-[2-(2-isobutoxycarbo...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity for NS3 protease K136RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122886BDBM50122886(4-(2-{2-[2-(4-Carboxy-2-isobutoxycarbonylamino-but...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122883BDBM50122883(3-Chloro-4-(2-{4,4-difluoro-2-[2-(2-isobutoxycarbo...)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity NS3 protease K136MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122879BDBM50122879(4-tert-Butoxycarbonylamino-4-(1-{1-[2-(2-chloro-ph...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122882BDBM50122882(4-(1-{1-[2-(2-Chloro-phenyl)-ethylcarbamoyl]-2-mer...)
Affinity DataKi:  7.30E+3nMAssay Description:Binding affinity for enzyme NS3 protease wild-typeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122882BDBM50122882(4-(1-{1-[2-(2-Chloro-phenyl)-ethylcarbamoyl]-2-mer...)
Affinity DataKi:  8.30E+3nMAssay Description:Binding affinity for enzyme K136RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122881BDBM50122881(3-(2-{2-[2-(4-Carboxy-2-isobutoxycarbonylamino-but...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122882BDBM50122882(4-(1-{1-[2-(2-Chloro-phenyl)-ethylcarbamoyl]-2-mer...)
Affinity DataKi:  1.35E+4nMAssay Description:Binding affinity for enzyme K136MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122885BDBM50122885(4-(2-{2-[2-(4-Carboxy-2-isobutoxycarbonylamino-but...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122896BDBM50122896(4-Isobutoxycarbonylamino-4-[1-(2-mercapto-1-phenet...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122905BDBM50122905(3-(2-{2-[2-(4-Carboxy-2-isobutoxycarbonylamino-but...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122889BDBM50122889(4-tert-Butoxycarbonylamino-4-[1-(2-mercapto-1-phen...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122906BDBM50122906(4-[1-(2-Mercapto-1-phenethylcarbamoyl-ethylcarbamo...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122880BDBM50122880(2-(2-{2-[2-(4-Carboxy-2-isobutoxycarbonylamino-but...)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122888BDBM50122888(4-(2-Acetylamino-3-carboxy-propionylamino)-4-[1-(1...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122891BDBM50122891(4-(2-{2-[2-(4-Carboxy-2-isobutoxycarbonylamino-but...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity for enzyme human leukocyte HLEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122882BDBM50122882(4-(1-{1-[2-(2-Chloro-phenyl)-ethylcarbamoyl]-2-mer...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity for enzyme human leukocyte HLEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122901BDBM50122901(2-(2-{2-[2-(4-Carboxy-2-isobutoxycarbonylamino-but...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122890BDBM50122890(4-tert-Butoxycarbonylamino-4-[1-(1-carboxy-2-merca...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122894BDBM50122894(4-[1-(1-Benzylcarbamoyl-2-mercapto-ethylcarbamoyl)...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Mrl Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122904BDBM50122904({1-[1-(2-Mercapto-1-phenethylcarbamoyl-ethylcarbam...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed