Compile Data Set for Download or QSAR
Report error Found 75 Enz. Inhib. hit(s) with all data for entry = 2876
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25680BDBM25680(4-[(5-bromo-1,3-thiazol-2-yl)amino]benzoic acid | ...)
Affinity DataIC50: 79nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25683BDBM25683(4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-(2-methoxyet...)
Affinity DataIC50: 97nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25681BDBM25681(4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-methylbenzam...)
Affinity DataIC50: 140nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25684BDBM25684(4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-(1-methoxypr...)
Affinity DataIC50: 330nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25678BDBM25678(N-{4-[(5-bromo-1,3-thiazol-2-yl)amino]phenyl}aceta...)
Affinity DataIC50: 360nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAromatase(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25658BDBM25658(5-bromo-N-(4-fluorophenyl)-1,3-thiazol-2-amine | a...)
Affinity DataIC50: 370nMAssay Description:Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) in the SelectScreen Kinase Profiling Service...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25658BDBM25658(5-bromo-N-(4-fluorophenyl)-1,3-thiazol-2-amine | a...)
Affinity DataIC50: 400nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAromatase(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25681BDBM25681(4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-methylbenzam...)
Affinity DataIC50: 440nMAssay Description:Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) in the SelectScreen Kinase Profiling Service...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25697BDBM25697(3-[(5-bromo-1,3-thiazol-2-yl)amino]benzoic acid | ...)
Affinity DataIC50: 440nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25660BDBM25660(N-(4-fluorophenyl)-5-iodo-1,3-thiazol-2-amine | am...)
Affinity DataIC50: 500nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25694BDBM25694(5-bromo-N-[3-(methylsulfanyl)phenyl]-1,3-thiazol-2...)
Affinity DataIC50: 500nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25669BDBM25669(4-[(5-bromo-1,3-thiazol-2-yl)amino]phenol | aminot...)
Affinity DataIC50: 510nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25676BDBM25676(1-N-(5-bromo-1,3-thiazol-2-yl)benzene-1,4-diamine ...)
Affinity DataIC50: 600nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25699BDBM25699(3-[(5-bromo-1,3-thiazol-2-yl)amino]-N-methylbenzam...)
Affinity DataIC50: 740nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25721BDBM25721(4-({6-[(5-cyano-1,3-thiazol-2-yl)amino]pyridin-3-y...)
Affinity DataIC50: 880nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25673BDBM25673(5-bromo-N-[4-(pyridin-4-yloxy)phenyl]-1,3-thiazol-...)
Affinity DataIC50: 900nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25693BDBM25693(5-bromo-N-(3-methoxyphenyl)-1,3-thiazol-2-amine | ...)
Affinity DataIC50: 900nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAromatase(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25680BDBM25680(4-[(5-bromo-1,3-thiazol-2-yl)amino]benzoic acid | ...)
Affinity DataIC50: 960nMAssay Description:Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) in the SelectScreen Kinase Profiling Service...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25685BDBM25685(4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-(2-methoxyet...)
Affinity DataIC50: 980nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25657BDBM25657(5-chloro-N-(4-fluorophenyl)-1,3-thiazol-2-amine | ...)
Affinity DataIC50: 1.10E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25691BDBM25691(5-bromo-N-(3-methylphenyl)-1,3-thiazol-2-amine | a...)
Affinity DataIC50: 1.10E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25662BDBM25662(5-bromo-N-phenyl-1,3-thiazol-2-amine | aminothiazo...)
Affinity DataIC50: 1.10E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25698BDBM25698(3-[(5-bromo-1,3-thiazol-2-yl)amino]-N-(2-methoxyet...)
Affinity DataIC50: 1.22E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25720BDBM25720(2-{[5-(morpholin-4-ylmethyl)pyridin-2-yl]amino}-1,...)
Affinity DataIC50: 1.40E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25672BDBM25672(5-bromo-N-(4-phenoxyphenyl)-1,3-thiazol-2-amine | ...)
Affinity DataIC50: 1.40E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25682BDBM25682(4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-(2-hydroxyet...)
Affinity DataIC50: 1.48E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25695BDBM25695(3-[(5-bromo-1,3-thiazol-2-yl)amino]benzonitrile | ...)
Affinity DataIC50: 1.50E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25674BDBM25674(1-{4-[(5-bromo-1,3-thiazol-2-yl)amino]phenyl}ethan...)
Affinity DataIC50: 1.70E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25670BDBM25670(5-bromo-N-(4-methoxyphenyl)-1,3-thiazol-2-amine | ...)
Affinity DataIC50: 1.70E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 5359BDBM5359(5-bromo-N-(pyridin-2-yl)-1,3-thiazol-2-amine | ACS...)
Affinity DataIC50: 2.00E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25668BDBM25668(4-[(5-bromo-1,3-thiazol-2-yl)amino]benzonitrile | ...)
Affinity DataIC50: 2.10E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25696BDBM25696(ethyl 3-[(5-bromo-1,3-thiazol-2-yl)amino]benzoate ...)
Affinity DataIC50: 2.25E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25688BDBM25688(4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-[2-(morpholi...)
Affinity DataIC50: 2.30E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25667BDBM25667(5-bromo-N-[4-(trifluoromethyl)phenyl]-1,3-thiazol-...)
Affinity DataIC50: 2.40E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 5362BDBM5362(ACS Chemical Biology 3180 Compound 63 | 2-(pyridin...)
Affinity DataIC50: 2.50E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25703BDBM25703(5-bromo-N-(2-methoxyphenyl)-1,3-thiazol-2-amine | ...)
Affinity DataIC50: 2.70E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25666BDBM25666(5-bromo-N-(4-methylphenyl)-1,3-thiazol-2-amine | a...)
Affinity DataIC50: 2.84E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25664BDBM25664(5-bromo-N-(4-bromophenyl)-1,3-thiazol-2-amine | am...)
Affinity DataIC50: 2.90E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25663BDBM25663(5-bromo-N-(4-chlorophenyl)-1,3-thiazol-2-amine | a...)
Affinity DataIC50: 3.00E+3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25701BDBM25701(5-bromo-N-(2-methylphenyl)-1,3-thiazol-2-amine | a...)
Affinity DataIC50: 3.00E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25717BDBM25717(5-bromo-N-(pyridin-3-yl)-1,3-thiazol-2-amine | ami...)
Affinity DataIC50: 3.60E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25722BDBM25722(2-({5-[(4-methylpiperazin-1-yl)methyl]pyridin-2-yl...)
Affinity DataIC50: 3.80E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25681BDBM25681(4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-methylbenzam...)
Affinity DataIC50: 4.27E+3nMAssay Description:Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) in the SelectScreen Kinase Profiling Service...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25723BDBM25723(2-({5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}...)
Affinity DataIC50: 4.40E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25687BDBM25687(4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-[2-(diethyla...)
Affinity DataIC50: 4.52E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25715BDBM25715(5-bromo-N-(naphthalen-1-yl)-1,3-thiazol-2-amine | ...)
Affinity DataIC50: 5.00E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25686BDBM25686(4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-[2-(dimethyl...)
Affinity DataIC50: 5.25E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25689BDBM25689(4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-[2-(pyrrolid...)
Affinity DataIC50: 5.32E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25724BDBM25724(2-[(5-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}py...)
Affinity DataIC50: 5.40E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Novartis

LigandChemical structure of BindingDB Monomer ID 25712BDBM25712(N-(5-bromo-1,3-thiazol-2-yl)benzamide | aminothiaz...)
Affinity DataIC50: 5.50E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
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