Compile Data Set for Download or QSAR
maximum 50k data
Found 43 Enz. Inhib. hit(s) with all data for entry = 50012827
Target3-phosphoshikimate 1-carboxyvinyltransferase(Escherichia coli (strain K12))
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123088(6,7-Dihydroxy-2-[1-(2-hydroxy-4-methoxy-phenyl)-me...)
Affinity DataKi:  100nMAssay Description:Competitive inhibitory activity of the compound was determined with respect to EPSP (5-enolpyruvylshikimate- 3-phosphate) synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoshikimate 1-carboxyvinyltransferase(Escherichia coli (strain K12))
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123114(2-[1-(4-Diethylamino-phenyl)-meth-(E)-ylidene]-6,7...)
Affinity DataKi:  650nMAssay Description:Competitive inhibitory activity of the compound was determined with respect to EPSP (5-enolpyruvylshikimate- 3-phosphate) synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123120(6,7-Dihydroxy-2-[1-(2-hydroxy-4-pentyloxy-phenyl)-...)
Affinity DataIC50:  220nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123099(2-[1-(4-Hexyloxy-2-hydroxy-phenyl)-meth-(E)-yliden...)
Affinity DataIC50:  320nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123103(2-[1-(4-Butoxy-2-hydroxy-phenyl)-meth-(E)-ylidene]...)
Affinity DataIC50:  450nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123101(6,7-Dihydroxy-2-[1-(2-hydroxy-4-propoxy-phenyl)-me...)
Affinity DataIC50:  510nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123096(6,7-Dihydroxy-2-[1-(2-hydroxy-4-isobutoxy-phenyl)-...)
Affinity DataIC50:  580nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123093(4-{4-[6,7-Dihydroxy-3-oxo-3H-benzofuran-(2E)-ylide...)
Affinity DataIC50:  650nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123087(6,7-Dihydroxy-2-[1-(2-hydroxy-3-methoxy-phenyl)-me...)
Affinity DataIC50:  800nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123118(6,7-Dihydroxy-2-[1-(2-hydroxy-phenyl)-meth-(E)-yli...)
Affinity DataIC50:  800nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123090(6,7-Dihydroxy-2-[1-[2-hydroxy-4-(4-hydroxy-butoxy)...)
Affinity DataIC50:  860nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123104(2-[1-(4-Benzyloxy-2-hydroxy-phenyl)-meth-(E)-ylide...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123108(6,7-Dihydroxy-2-[1-(2-hydroxy-4-isopropoxy-phenyl)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123111(4-{4-[6,7-Dihydroxy-3-oxo-3H-benzofuran-(2E)-ylide...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123085(4-{4-[6,7-Dihydroxy-3-oxo-3H-benzofuran-(2E)-ylide...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123124(2-[1-(4-Butoxy-phenyl)-meth-(E)-ylidene]-6,7-dihyd...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123121(6,7-Dihydroxy-2-[1-[2-hydroxy-4-(6-hydroxy-hexylox...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123088(6,7-Dihydroxy-2-[1-(2-hydroxy-4-methoxy-phenyl)-me...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123098(CHEMBL134581 | {2-[6,7-Dihydroxy-3-oxo-3H-benzofur...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123089(6,7-Dihydroxy-2-[1-(2-nitro-phenyl)-meth-(E)-ylide...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123109(6,7-Dihydroxy-2-[1-[2-hydroxy-4-(3-hydroxy-propoxy...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123116(CHEMBL135330 | {4-[6,7-Dihydroxy-3-oxo-3H-benzofur...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123113(2-[1-{4-[Ethyl-(2-hydroxy-ethyl)-amino]-2-methyl-p...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123106(6,7-Dihydroxy-2-[1-phenyl-meth-(E)-ylidene]-benzof...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123095(6,7-Dihydroxy-2-[1-o-tolyl-meth-(E)-ylidene]-benzo...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123100(6,7-Dihydroxy-2-[1-(4-nitro-phenyl)-meth-(E)-ylide...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123123(2-[1-(4-Diethylamino-2-hydroxy-phenyl)-meth-(E)-yl...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123112(6,7-Dihydroxy-2-[1-(4-imidazol-1-yl-phenyl)-meth-(...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123086(2-[1-(2-Chloro-phenyl)-meth-(E)-ylidene]-6,7-dihyd...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123115(6,7-Dihydroxy-2-[1-(4-pyrrolidin-1-yl-phenyl)-meth...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123097(2-[1-(4-Ethoxy-phenyl)-meth-(E)-ylidene]-6,7-dihyd...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123125(6,7-Dihydroxy-2-[1-(4-trifluoromethyl-phenyl)-meth...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123114(2-[1-(4-Diethylamino-phenyl)-meth-(E)-ylidene]-6,7...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123110(CHEMBL434823 | {4-[6,7-Dihydroxy-3-oxo-3H-benzofur...)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123102(2-[6,7-Dihydroxy-3-oxo-3H-benzofuran-(2E)-ylidenem...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123122(6,7-Dihydroxy-2-[1-(4-methoxy-phenyl)-meth-(E)-yli...)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123119(6,7-Dihydroxy-2-[1-(4-hydroxy-phenyl)-meth-(E)-yli...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123117(6,7-Dihydroxy-2-[1-(2-trifluoromethyl-phenyl)-meth...)
Affinity DataIC50:  1.73E+4nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123105(4-[6,7-Dihydroxy-3-oxo-3H-benzofuran-(2E)-ylidenem...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123107(2-[1-(4-Dimethylamino-phenyl)-meth-(E)-ylidene]-6,...)
Affinity DataIC50:  2.59E+4nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123094(6,7-Dihydroxy-2-[1-(4-morpholin-4-yl-phenyl)-meth-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123091(2-[1-(4-Fluoro-phenyl)-meth-(E)-ylidene]-6,7-dihyd...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChorismate synthase(Streptococcus pneumoniae)
Pantherix

Curated by ChEMBL
LigandPNGBDBM50123092(6,7-Dihydroxy-2-[1-(2-methoxy-phenyl)-meth-(E)-yli...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibitory concentration against Streptococcus pneumoniae chorismate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed