Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50042185
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50421639(CHEMBL2110195)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124117((Z)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  2nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124112((E)-3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-(2,...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of VLA-4 to VCAM-1 binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50421639(CHEMBL2110195)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of VLA-4 to VCAM-1 binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124114((Z)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  5nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124107((Z)-2-[(2-Chloro-pyridine-3-carbonyl)-amino]-3-{4-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of VLA-4 to VCAM-1 binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124117((Z)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  25nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124116(2-(2-Chloro-pyridin-3-yl)-8-[(3,5-dichloro-pyridin...)
Affinity DataIC50:  55nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124115((E)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  60nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124111((E)-2-[(2-Chloro-pyridine-3-carbonyl)-amino]-3-{4-...)
Affinity DataIC50:  66nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124107((Z)-2-[(2-Chloro-pyridine-3-carbonyl)-amino]-3-{4-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of VLA-4 to VCAM-1 binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124112((E)-3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-(2,...)
Affinity DataIC50:  80nMAssay Description:Inhibition of VLA-4 to VCAM-1 binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124114((Z)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  140nMAssay Description:Inhibition of VLA-4 to VCAM-1 binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124109((Z)-2-[(2-Chloro-pyridine-3-carbonyl)-amino]-3-[4-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of VLA-4 to VCAM-1 binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124115((E)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  200nMAssay Description:Inhibition of VLA-4 to VCAM-1 binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124106((Z)-2-[(2-Chloro-pyridine-3-carbonyl)-amino]-3-[4-...)
Affinity DataIC50:  220nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124108((E)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  400nMAssay Description:Inhibition of VLA-4 to VCAM-1 binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124116(2-(2-Chloro-pyridin-3-yl)-8-[(3,5-dichloro-pyridin...)
Affinity DataIC50:  410nMAssay Description:Inhibition of VLA-4 to VCAM-1 binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124113((E)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124105((Z)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124110((Z)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of VLA-4 to VCAM-1 binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124110((Z)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124106((Z)-2-[(2-Chloro-pyridine-3-carbonyl)-amino]-3-[4-...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124118((E)-2-[(3-Acetyl-thiazolidine-4-carbonyl)-amino]-3...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of VLA-4 to VCAM-1 binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124111((E)-2-[(2-Chloro-pyridine-3-carbonyl)-amino]-3-{4-...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of VLA-4 to VCAM-1 binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124109((Z)-2-[(2-Chloro-pyridine-3-carbonyl)-amino]-3-[4-...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124113((E)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of VLA-4 to VCAM-1 binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124108((E)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124105((Z)-2-[((R)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibition of VLA-4 to VCAM-1 binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50124118((E)-2-[(3-Acetyl-thiazolidine-4-carbonyl)-amino]-3...)
Affinity DataIC50:  8.30E+4nMAssay Description:Inhibition of VLA-4 to VCAM-1 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed